bioinformatics_4_sem..

Transkrypt

ROZWÓJ POTENCJAŁU I OFERTY DYDAKTYCZNEJ POLITECHNIKI WROCŁAWSKIEJ
BIOTECHNOLOGY
Bioinformatics
II Level – MSc (4 semesters, 120 ECTS)
PROGRAM
4 SEMESTERS
MSc
Entry requirements:
Completed:
Diploma Level I Studies in:
Master Thesis
Chemistry, Biotechnology
Possible extension:
Studies of Level III (PhD)
Final Exam
Graduate:
The graduate should be theoretically
and practically prepared to apply
biotechnological techniques to
analyze genetic data, model
biomolecular systems and processes,
design drugs, biocatalysts, biosensors
applied in analysis, diagnostics,
biosynthesis and bioremediation. The
combination of the basic knowledge of
design of bioprocesses and
bioproducts with computational skills
are aimed to prepare graduates for
work in the quality control or research
laboratories, environment protection,
chemical, food and the
pharmaceutical industry.
Projekt współfinansowany ze środków Unii Europejskiej w ramach
Europejskiego Funduszu Społecznego
PLAN OF STUDIES
1st YEAR, supplementary SEMESTER
Obligatory courses:
ECTS
Form of
Assessme
nt
Contact hours/week
No.
Code
Subject/Module
L
1
Mechanical
Engineering
2
2
Materials Science
2
3
Safety Engineering
1
4
Metrology and
Automatic Control
1
5
Chemical
Technology – Raw
Materials and
Carriers of Energy
1
Basic Unit
Processes in
Chemical
Technology
2
Electrical and
Electronic
Engineering
2
6
7
8
T
P
S
1
1
2
TSW
45
90
3
T
30
90
3
T
30
60
2
T
45
90
3
T
60
90
3
E
60
150
5
E
60
150
5
T
30
60
2
CW
30
90
3
T
3
2
2
Technical
Drawings –
Drafting
9
lab
CHS
2
Principles of
Chemical
Engineering
2
Optional courses I/ Choose one module
CHS
TSW
ECTS
Form of
Assessme
nt
15
50
2
T
Contact hours/week
No.
10
Code
Subject/Module
L
T
lab
P
s
1
Polymers in
medicine
TOTAL
14
12
1
0
405 930
31
1st YEAR, SEMESTER 1
Obligatory courses:
CHS
TSW
ECTS
Form of
Assessme
nt
60
150
5
E
30
90
3
E
30
90
3
T
60
150
5
T
30
60
2
CW
2
60
150
5
E
4
60
120
4
CW
CHS
TSW
ECTS
Form of
Assessme
nt
30
90
3
T
Contact hours/week
No.
Code
1
Subject/Module
Theoretical and
Computational
Chemistry
Principles and
Practical Aspects of
Medicinal Chemistry
2
3
L
2
2
4
Molecular
Dynamics
2
5
Networks and
Workstations with
the UNIX Systems
Bioinformatics
7
Applied Informatics
lab
P
s
2
2
Methodology of
Experimental
Research
6
T
2
2
2
Optional courses I
Choose one or two modules
Contact hours/week
No.
Code
Subject/Module
L
T
lab
2
P
s
8
Polish Cultural and
Historical studies
9
Polish Language
for Foreign
Students
2
30
60
2
CW
10
Foreign Language
4
60
120
4
CW
TOTAL
10
6
10
390
900
30
1st YEAR, SEMESTER 2
Obligatory courses:
CHS
TSW
ECTS
Form of
Assessme
nt
60
150
5
E
60
150
5
E
45
120
4
T
30
60
2
CW
30
90
3
T
45
120
4
E
30
60
2
CW
60
120
4
T
15
30
1
CW
Contact hours/week
No.
Code
Subject/Module
L
T
lab
Spectroscopic
Methods in Medicinal
Chemistry
2
2
Molecular Modeling
1
2
3
Instrumental Drug
Analysis
1
2
4
Retrieval of Scientific
and Technical
Information
1
s
2
1
2
5
Principles of Drug
Design
2
6
Bionanotechnology
2
7
Advanced Programming
and Numerical Methods
2
8
Research Laboratory
4
9
Graduate Seminar
TOTAL
p
1
1
8
14
3 375
900
30
2nd YEAR, SEMESTER 3
Obligatory courses:
CHS
TSW
ECTS
Form of
Assessme
nt
30
60
2
T
Contact hours/week
No.
Code
Subject/Module
1
L
Quality
Management
Systems
2
T
lab
p
S
2
Intellectual Property
Rights and Ethical
Questions in
Biotechnology
2
30
60
2
T
3
Terrestial Ecology
2
30
60
2
T
4
Design of
Biotechnological
Processes
2
30
60
2
T
225
300
10
CW
15
300
10
E
CHS
TSW
ECTS
Form of
Assessme
nt
30
60
2
T
5
Graduate
Laboratory
15
Graduate Seminar
and Thesis
Preparation
5
1
Optional courses II
Choose one module
Contact hours/week
No.
Code
Subject/Module
1
Selforganization in
Chemistry
TOTAL
L
L
T
lab
P
T
lab
P
S
2
8
15
2
1
390 900
30
S
L – Lecture T – Tutorials, l – laboratory, p – project, s – seminar,
CHS
TSW
CHS – Contact Hours (organized), TSW – Total Student Workload (h), E – Exam, T – Test, CW – Course Work
Description of the courses
MECHANICAL ENGINEERING
Language: English
Year (I), semester (0)
Level: II
Prerequisites: Engineering Graphics
Course: Basic
Obligatory
Teaching:Traditional
Lecturers: Marek Gawliński PhD, Eng, DSc, Associate professor,
Maciej Chorowski PhD, Eng, DSc, Associate professor
Hours / sem. (h)
Exam / Course work:
ECTS
Workload (h)
Lecture
30
T
2
60
Tutorials
Laboratory
Project
15
CW
1
30
Seminar
Outcome: The Graduates would possess knowledge regarding the fundamentals of
engineering design, materials, transfer of forces, moments and power by means of joints,
couplings and brakes, bearings and transmission. The project will be focused on
teamwork and on problems solving.
Content: Mechanical engineering as an interesting profession, nature of engineering
design, examples of engineers activity. Introduction to design process, methodology of
mechanical designing, safety considerations. Materials in engineering processes,
material selection charts. Effects of material properties on design. Common materials;
steel, nonferrous alloys, plastics, aging and fatigue of materials: case history, Standards,
quality and reliability of design, life cycle cost of products, fits and tolerances, design for
manufacturing purposes and assembly, Transmission of forces; concept of force flow,
stress and deformation, stress concentration, Design of temporary and permanent
joints; bolted, welded and frictional. Temperature and pressure considerations. Failures a
case history. Transmission of motion; speed reduction or multiplication, rotating or
reciprocating motion, belt and gear transmissions. Transmission of moments: design
and operating mode of couplings. Transmission of moments; shafts, damping of
vibrations, failures, including case histories. Transfer of loads; ball bearings, sliding
bearings, friction and wear, failures including case histories, Thermal processes in
mechanical engineering; heat transfer, thermal expansion, insulations, materials creep.
Thermal processes in mechanical engineering: failures and case histories (low & high
temperatures).
Literature:
1. Juvinal R. C., Marshek K. M., "Fundamentals of Machine Component Design" 4th
Edition, John Wiley & Sons, Inc., 2006,
2. Moaveni Saeed "Engineering Fundamentals – An Introduction to Engineering", Thomson
Canada Ltd., 2005,
3. Farag M. M., "Materials and Process Selection for Engineering Design", CRC Press, 2nd
Edition, 2007,
4. Klebanov B. M., "Machine Elements, Life and Design", CRC Press, 2007,
MATERIALS SCIENCE
Language: English
Prerequisites: Physics
Course: Basic
Obligatory
Level: II
Lecturers: B. Szczygieł, PhD, Eng, DSc, Associate Professor
J. Pigłowski, PhD, Eng, DSc, Associate Professor
Hours / sem. (h)
Exam / Course work:
ECTS
Workload (h)
Lecture
30
T
3
90
Tutorials
Laboratory
Project
Seminar
Outcome: Acquiring methods; polymers, metallic materials and ceramics. Selection of
engineering materials for specific applications. Modification of material properties through
structure modification. Anticipated material behaviors during exploitation, basing on their
physical, chemical and mechanical properties. Selection of anticorrosive protection.
Content: Elementary information within the areas of metallic materials, polymers and
ceramics. The ordination and classification of engineering materials. Structures of
amorphous and crystalline solids. Definitions of elementary mechanical properties of
construction materials that affect their practical applications. Phase diagrams and phase
transitions. Degradation of materials and methods of the prevention of corrosion.
Classification of materials. Modern materials needs. Atomic structures. Atomic bonding.. The
structure of cristalline solids. Imperfections in solids; point defects, dislocations, interfacial
defects. Mechanical properties of metals. Stress-strain behavior. Elastic deformation. Plastic
deformation. Tensile test. Hardness, impact resistance, crack resistance, fatigue, creep.
Phases. Phase rule. Equilibrium phase diagrams. Steel; fabrication, components and
classification. Constructional steel. Tool steel. Stainless steel. Heat treatment of steel. Cast
iron. Non-ferrous metals and their alloys. Corrosion of metals. Corrosion rate. Forms of
corrosion. Corrosion prevention. Structures and properties of ceramics and glass. Polymer
based industry, applications, perspectives. Nomenclature and classification scheme.
Condensed state (amorphous and semicrystalline polymers). Viscoelastic properties of
polymers (rheological models). Investigation methods for polymers.. Polymer blends and
alloys. Polymer composite.
Literature:
1. W. D. Callister Jr, Materials science and engineering, John Wiley & Sons, Inc., New York,
1991.
SAFETY ENGINEERING
Language: English
Prerequisites:
Course: Basic
Obligatory
Level: II
Lecturers: Z. Meissner, PhD, Eng
Hours / sem. (h)
Exam / Course work:
ECTS
Workload (h)
Lecture
15
T
1
30
Tutorials
Laboratory
15
CW
1
30
Project
Seminar
Outcome: Elementary information on safety hazards in chemical plants and on prevention
of accidents, as well as mitigation of losses. Presentation of international regulations relating
to safety hazards.
Content: Basic information about safety hazards in chemical plants and prevention of
accidents. Major accidents involving dangerous substances. International convention
concerning the disaster prevention. EC directive. Classification of dangerous substances .
Fires, explosions, toxic release. Procedures applied in the analysis of safety risk, Elements
of the risk analysis.
Methodology and techniques of accidents preventing, Safety
management.
Literature:
1. Medard L.A., Accidental explosions, Eblis Horwood Limited, 1989.
CODE
METROLOGY AND AUTOMATIC CONTROL
Language: English
Level: II
Course: Basic
Obligatory
Lecturer: Andrzej Muciek, PhD, Eng, DSc, Associate Professor
Hours / sem. (h)
Exam / Course work/T:
ECTS
Workload (h)
Lecture
15
T
1
30
Tutorials
Laboratory
30
CW
2
60
Project
Seminar
Outcome:
Understanding principles of operation, characteristics and application of
instrumentation for industrial measurements and control. Methods of the selection of the type
of an automatic control for system in chemical industry. Methods of estimation and
improvement of quality control.
Content: Feedback fundamentals. Block diagrams. Structures of control systems and
automatic control systems. Basic dynamic blocks of automatic control systems,
determination of dynamic modeling by means of step response. Sensors for measurement of
temperature, pressure, intensity of flow and the liquid level. Characteristics, basic
parameters, application. Intelligent sensors of non-electrical quantities, measuring
converters, conditioning modules for computers and the digital interfaces. Two-level
automatic control, continuous and pulse-step control. Stability and quality of the automatic
control process. Actuators, Rules for choosing controller type and controller settings.
Computer simulation in design of automatic control systems including examples of some
computerised automatic control systems.
Literature:
1. E. O. Doebelin, Measurement Systems Application and Design, Mc Graw-Hill Comp, Inc.,
2004, 1990, 1983.
CODE
CHEMICAL TECHNOLOGY – RAW MATERIALS AND CARRIERS OF ENERGY
Language: English
Course: Basic
Level: II
Obligatory
Lecturer: Grazyna Gryglewicz, PhD, Eng, DSc,Professor
Staff:, E. Lorenc- Grabowska, PhD, K. Kierzek, PhD, K. Jaroszewska,, PhD, R. Łużny, PhD
Lecture
Tutorials
Laboratory
Project
Hours / sem. (h)
15
45
E
CW
ECTS
1
2
Workload (h)
30
60
Seminar
Outcome: Technological knowledge in the field of characterization of raw materials and their
utilization in chemical industry.
Content: Origin, recovery and constitution of fossil fuels and biomass. Evaluation of raw materials for
use as feedstock for chemical processing. Fuels; manufacture, composition, properties and utilization.
Occurrence, reserves and exploitation of coal. Origin of coal. Coal processing. Moisture and mineral
matter in coal. Petrographic composition. Composition of organic coal substances. Technological
properties of coal as a energy source and a raw material for chemical processing. Coal classification.
Biomass as chemicals and energy source. Occurrence, reserves and exploitation of petroleum and
natural gas. Origin of petroleum and natural gas. Chemical and technological classification system of
petroleum. Hydrocarbon and non-hydrocarbon constituents of petroleum. Separation of petroleum.
Petroleum a supply source for petrochemicals and fuels. Natural gas, purification and chemicals from
natural gas. Environmental failure in exploitation, transportation and processing of petroleum and
natural gas.
Literature:
1. D.W. Van Krevelen, Coal – Typology, Physics, Chemistry, Constitution, Elsevier,
Amsterdam, 1993
2. J.G. Speight: The Chemistry and technology of coal, Marcel Dekker, Inc. New York
1994
3. J.G. Speight: The Chemistry and technology of petroleum, Marcel Dekker, Inc. New York
1991
4. R.A. Meyers: Handbook of petroleum refining processes. Second edition.Mc Graw Hill.
Boston 1997.
CODE
BASIC UNIT PROCESSES IN CHEMICAL TECHNOLOGY
Language: English
Course: Basic
Level: II
Obligatory
Lecturers: J. Walendziewski, PhD, Eng, DSc, Associate Professor,
M. Bryjak, PhD, Eng, DSc, Associate Professor
Hours / sem. (h)
ECTS
Workload (h)
Lecture
30
E
3
90
Tutorials
Laboratory
30
CW
2
60
Project
Seminar
Outcome: Education based on the selection of a unit process type according to
dependence on the reaction type and process parameters.
Content: The course provides information regarding several of the most important unit
processes applied in chemical technology taking into account process continuity, reactor
design, catalyst presence (or thermal) in broad process parameters. The students will be
familiarized with selected processes during the course of laboratory experiments. Periodic
processes, semi-continuous processes, continuous processes, egzo and endothermic
processes, high temperature processes, catalytic processes, hydrogen pressure processes,
solid and liquid fuel gasification processes, fluid and moving bed processes, gas phase
processes, polymerization enzymatic catalytic processes, fermantation procsses. separation
processes, hybrid processes.
CODE
ELECTRICAL AND ELECTRONIC ENGINEERING
Language: English
Course: Basic
Level: II
Obligatory
Lecturer:
Andrzej Muciek, PhD, Eng, DSc, Associate Professor,.
Hours / sem. (h)
ECTS
Workload (h)
Lecture
30
T
3
90
Tutorials
Laboratory
30
CW
2
60
Project
Seminar
Outcome: Understanding the operation principles and rules in application of basic electric
and electronic equipment, including supplying devices, electronic measuring instrumentation
and automatic control systems.
Content: The operating principles, basic parameters and applications of electrical and
electronic instrumentation are presented to students, particularly voltage and current
sources, voltmeters, power and signal generators, DC and AC motors, impedance meters,
instrumentation amplifiers. Students get practical training in exploitation of electronic
measuring equipment. Basic methods of analysis of direct current circuits and alternate
current circuits, as well as, a computer simulation of the operation of electronic analogue
circuits, analysis and parameters estimation, are presented. Basic ideas, the operation
principle, the mathematical description and rules of application of digital logic elements are
given, combined with computer simulation. Students study operating principles and functions
of microprocessors in modern electronic instrumentation. Students experimentally investigate
selected electronic circuits, most widely used as an interface to sensors.
Literature:
1. J.H Bentley, K. M. Hess, A Programmed Review for Electrical Engineering, Van Nostrand
Reinhold Company, New York 1995.
CODE
TECHNICAL DRAWING-DRAFTING
Language: English
Level: II
Prerequisites: basic knowledge of computers use
Course: Basic
Obligatory
Lecturers: I. Polowczyk, PhD, Eng
Lecture
Hours / sem. (h)
ECTS
Workload (h)
Tutorials
Laboratory
30
CW
2
60
Project
Seminar
Outcome: The students will familiarize themselves with Computer Aided Design of
engineering objects and have a working knowledge of Autodesk Mechanical Desktop and
Autodesk Inventor.
Content: The topics of the course include axonometric and ortographic projections. During
the course students will become familiar with the rules of making sections, and with the
definition of intersection lines. Besides the descriptive geometry, the programme includes
fundamentals of technical drawing, such as dimensioning, tolerance and fitting, types of
joints, assembly and working drawings. During the course will students prepare drawings
using the CAD programs. In addition, technical drawing (types of drawing, drawing size,
types and thickness of lines, fonts), projection of 2D and 3D objects (axonometric and
ortographic methods), basics of Computer Aided Design (introduction to CAD-systems;
working space, drawing modus and modus of edition), setting of desired parameters of CAD
program (layer management, setting of attributes, co-ordinate systems), presentation of
object’s appearance (types of sections), graphical representation of intersecting 3D objects,
dimensioning of objects (dimensioning signs and notations, rules of dimensioning), tolerance
of dimensions, fitting of elements, deviations of shape, position and surface roughness, will
be introduced. The course will give an outline on types of joints, design drawing (assembly
and working drawings) and drawing of chemical equipment.
Literature:
1. Tadeusz Dobrzański – Rysunek Techniczny, WNT, Warszawa 1997
2. A.Pikoń: AutoCAD 2007PL- pierwsze kroki, Helion, Gliwice 2006
3. Joanna Matelkin, Andrzej Setman, Paweł Zdrojewski – MegaCad 1.5, Helion, Gliwice
1999
CODE
PRINCIPLES OF CHEMICAL ENGINEERING
Language: English
Level: II
Prerequisites: Basic Physics
Course: Basic
Obligatory
Lecturers: Prof. Andrzej Kmieć, PhD, Eng, DSc
Hours / sem. (h)
ECTS
Workload (h)
Lecture
30
Tutorials
Laboratory
Project
Seminar
3
90
Outcome: Definitions and solutions of fundamental engineering problems and methods of
unit operation realization.
Content: Momentum, heat and mass transport phenomena. Hydrodynamics. Unit operation
and equipment for their realization purposes. Balance principles of streams and apparatus.
Laws of conservation, Bernoullie’s law and its applications, flow resistance, pumps
(characteristics and applications), transport of gases and solids, sedimentation, settlers,
filtration, equipment, dust removal, mixing and mixers. Heat conduction and convection, total
heat transfer coefficient, heat exchangers. Mass transport, kinetics, modeling. Multi-step
processes, diffusion processes and chemical reactors.
Literature:
1. R. Koch, A. Noworyta: Procesy mechaniczne w inżynierii chemicznej, WNT, 1995
2. T. Hobler: Ruch ciepła i wymienniki, WNT 1971
3. Z. Kembłowski,
1985
Podstawy teoretyczne inżynierii chemicznej i procesowej , WNT
CODE
POLYMERS IN MEDICINE
Language: English
Level: II
Prerequisites:
Course: Advanced
Optional
Lecturer: Marek Bryjak, PhD, Eng, DSc, Associate Professor,
Hours / sem. (h)
ECTS
Workload (h)
Lecture
15
T
2
60
Tutorials
Laboratory
Project
Seminar
Outcome: The advantages and likelihood of using polymers in biotechnology and medicine.
General overview of polymers, their synthesis, structures and properties. The utilization of
polymers in selected areas of medical treatment.
Contents: The History of polymers an the impact of polymers on the way we live.
Polymerisation, copolymerisation, grafting, plasma polymerisation. Molecular weights,
number and weight average, polydispersity, methods of molecular weight evaluation,
solutions of polymers, Flory-Huggins model, blends of polymers, block copolymers,
interpolymers, phase transitons, amorphic and semicrystalline polymers. Surface properties
of polymers, surface energetics, and methods of surface investigation. Diffusion in polymers
and polymer membranes. Artificial organs (kidney, liver, lung, pancrease), polymer
orthopedic elements, polymers in dentistry, tissue engineering, scaffolds, controlled release
drugs, targeted drugs. Polymers with improved affinity and molecularly imprinted materials,
surgical materials, smart polymers, polymers with memory, polymeric supports and (!!!Polm.
as?) carriers for bioactive molecules.
Literature:
1. H.G.Elias, Macromolcules, Plenum Press, New York 1984,
2. L.Sperling, Polymer physicochemistry, Elsevier, New York, 1992
CODE
THEORETICAL AND COMPUTATIONAL CHEMISTRY
Language: English
Course: Advanced
Level: II
Obligatory
Prerequisites: Physics, Physical Chemistry
Teaching:Traditional/Distance L
Lecturers: prof. S. Roszak, PhD, Eng, DSc,
Staff: Krzysztof Strasburger, PhD, Eng, DSc
Hours / sem. (h)
Exam / Course work/T: E
ECTS
Lecture
30
3
Tutorials
30
CW
2
Laboratory
Project
Seminar
Workload (h)
90
60
Outcome: The students will have a working knowledge of the basics of quantum chemistry, with an
emphasis on its practical applications. The course also provides an understading of theoretical
predictions of properties for molecules, complexes, and molecular materials,in addition to modeling of
chemical processes.
Contents: The computational methods of quantum chemistry will describe electronic and
structural properties of molecules. The modern computational techniques which allow the
utilization of the theoretical chemistry for solutions of a large number of problems in
chemistry, biology, and material science. The course also provides information regarding the
application of quantum mechanics in model systems, as well as, describes the methods
currently being applied to the study of the electronic structures of molecular systems.
Literature:
1. M. A. Ratner, G. C. Schatz, Introduction to Quantum Mechanics in Chemistry,
Prentic--Hall;
2. L. Piela, Ideas of Quantum Chemistry, Elsevier, 2007
3. M. A. Ratner, G. C. Schatz, Introduction to Quantum Mechanics in Chemistry, Prentice Hall;
4. J. B. Foresman, A. Frisch, Exploring Chemistry with Electronic Structure Methods, Gaussian,
Inc.
CODE
PRINCIPLES OF PRACTICAL ASPECTS OF MEDICINAL CHEMISTRY
Language: English
Course: Advanced
Level: II
Obligatory
Prerequisites: Organic Chemistry
Lecturer: J. Oleksyszyn, PhD, Eng, DSc, Associate Professor,
Hours / sem. (h)
ECTS
Workload (h)
Lecture
30
Tutorials
Laboratory
Project
Seminar
3
90
Outcome: Description of the drug market and legal regulations. GMP. Generic drugs. Drug
classification. New drug discovery methods. New experimental therapeutics. Gene therapy.
siRNA. Monoclonal antibodies. New drugs on the market 2002-2006.
Contents: Description of the drug market and legal regulations. GMP. Generic drugs.
Recombinant proteins. Drug classification. New and classical drug discovery methods. New
experimental therapies. Gene therapy. siRNA. Monoclonal antibodies. New drugs on the
market 2004-2007. Drug market, USA, EU, Poland. Patent law. Orphan drug status.
Regulation concerning introduction of a new drug on the market. Clinical Trials. New drug
discovery methods. Natural compounds, combinatorial chemistry, rational drug design, SAR
and modern computer methods. Recombinant protein and monoclonal antibodies. Drug
classification. Enzyme inhibitors as drugs. Drugs as antagonist and agonist of the receptors.
Drugs interacting with DNA. Anticancer drugs. Drug metabolism. Prodrugs and drugs
delivery systems. New experimental therapies. Examples of new drugs on the market 20042007.
Literature:
1. R.B. Silverman, The organic chemistry of drug design and drug action, Academic Press,
Inc.,1992
2.
Comprehensive Medicinal Chemistry, Pergamon Press, 1994
CODE
METHODOLOGY OF EXPERIMENTAL RESEARCH
Language: English
Course: Advanced
Level: II
Obligatory
Prerequisites:
Teaching:Traditional/Distance L
Lecturers: W. Goldeman, PhD, Eng, M. Sieńczyk, PhD, Eng
Hours / sem. (h)
ECTS
Workload (h)
Lecture
30
Tutorials
Laboratory
Project
Seminar
3
90
Outcome: The course provides the fundamental knowledge regarding the main techniques
and concepts of qualitative and quantitative methods of experimental research in the area of
chemistry and biochemistry.
Contents: Understanding of the basic methodology in experimental research. Selection of
research subject and review of the literature. Techniques of proper sampling and standard
error of the mean. Levels of measurement and their types. Uncertainty in measurement.
Variables, research design and control of an error, confidence level. Interpretation and
analysis of the results. Models and hypothesis formation and methods of their validation.
Choosing the statistical tests and correlation techniques. Writing the experimental reports
and making useful experimental notes. Tracking own research progress without any errors.
How to organize a successful research group. Time and project management. Problems and
ideas highlighted above will be supported by several selected examples from chemistry and
biochemistry. Some aspects of ethics in science will be discussed.
Literature:
1.R. B. Burns, Introduction to research methods, SAGE Publications Ltd, 2000.
2.C. Fini, A. Floridi, V. N. Finelli, Laboratory Methodology in Biochemistry, CRC Press, 1989.
CODE
MOLECULAR DYNAMICS
Language: English
Level: II
Prerequisites: Physical Chemistry
Course: Basic
Obligatory
Teaching:Traditional/Distance L.
Lecturers: Tadeusz Andruniów, PhD, DSc, Associate professor
Hours / sem. (h)
ECTS
Workload (h)
Lecture
30
Tutorials
Laboratory
Project
Seminar
30
CW
3
90
2
60
Outcome: Basic knowledge required in order to understand molecular simulations using
molecular dynamics methods.
Content: The purpose of this course is to introduce classical mechanical methods used to
simulate the structure and dynamics of biomolecules. Molecular mechanics, molecular
dynamics, Langevin dynamics and Monte Carlo simulation methods will be addressed.
Potential energy functional forms, force fields, parametrization strategies, optimization
algorithms, phase space and trajectories, cutoffs and periodic boundary conditions, timeintegration algorithms, dynamical analysis, annealing and quenching and statistical
ensambles
Literature:
1. D. Frenkel i B. Smith: Understanding Molecular Simulation
2. M. P. Allen i D. J. Tildesley, Computer Simulation of Liquids
CODE
NETWORKS AND WORKSTATIONS WITH UNIX SYSTEM
Language: English
Course: Basic
Level: II
Obligatory
Prerequisites: Basic Computer Science
Lecturer: Krzysztof Strasburger, PhD, DSc, Eng
Lecture
Hours / sem. (h)
ECTS
Workload (h)
Tutorials
Laboratory
Project
Seminar
30
CW
2
60
Outcome: Acquiring skills by using the software tools available in the Unix environment; learning
mechanisms of using remote applications, acquiring the knowledge needed for basic system
administration.
Contents: The course is devoted to the basic rules of working of the Unix-family system. The
participants add new elements to their own systems following by discussion with the supervisor. The
course is wholly based on free software, for example the Linux operating system is used. Beginning
and finishing the session; shell, walking through the directory tree, programs and processes, signals,
types of files, rights, copying, moving and deleting files, creating links to files, vi and joe text editors,
The init program and system configuration, user accounts: the files password and shadow. Groups,
configuring the individual user environment and building the directory tree: the mount program and the
fstab file. Data archivization, basic rules of a network with the internet protocol, internet addresses and
names: using the DNS. The X11 graphic environment and making the network services available: the
inetd program. Working on remote computers (telnet) and transfering files (ftp), remote environment
with an encrypted communication channel: ssh. Electronic mail (running the server), www browsers
and servers; running own www servers, printing files, the programs lpd and ghostscript.
Literature:
1. J. Peek, J. Strang,, G.Todino-Gonguet, Learning the UNIX operating system, O'Reilly, 2002.
CODE
BIOINFORMATICS
Language: English
Level: II
Prerequisites: Biochemistry or Molecular Biology
Course: Advanced
Obligatory
Lecturers: P. Kędzierski, PhD, Eng, E. Dyguda-Kazimierowicz, D, DSc, Eng
Hours / sem. (h)
ECTS
Workload (h)
Lecture
30
Tutorials
Laboratory
Project
Seminar
30
CW
3
90
2
60
Outcome: Understanding of bioinformatics methods, their applicability and limits in the fields of
comparative sequence analysis, similarity-based data mining, and the prediction of structure and
function. Introduction to modern genetic and biomedical research methods, including DNA and protein
microarray techniques. Acquiring computer skills suitable for solving computational biology and
biochemistry problems using bioinformatics tools and services. Usage of computer databases for
sequence, structure and other biotechnological data. Practical skills to analyse biological information;
comparative analysis of biological sequences, prediction of the gene and protein level structures and
the function from a sequence, analysis of molecular evolution and phylogenesis.
Contents: Theoretical basis of bioinformatics, starting from measures of sequence similarity
and relation to homology, through comparative analysis algorithms, to the assessment of
structure, function and molecular evolution of biomolecules combined with the elements of
contemporary biomedical research methods based on DNA and protein array technology.
Biotechnology databases; genetics, literature, biological sequences, biomolecular structures
and biological activity, sequence/structure similarity and homologous proteins. Methods of
analysis of bioinformatics data (e.g., sequences, structures) accompanied by the
visualization of the results. Algorithms of comparative sequence analysis. Structure
prediction of biomolecules (homology based and “ab initio”). Introduction to microarray-based
methods; expression and proteome analysis.
Literature:
2. S.Q. Ye, Bioinformatics. A practical approach, Chapman & Hall/CRC, 2008
3. A.D. Baxevanis, B.F.F. Oullette, Bioinformatics, Wiley, 2001.
4. I. Eidhammer, I. Johanssen, W.R. Taylor, Protein Bioinformatics - an algorythmic
approach to sequence and structure analysis, Wiley, 2004
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APPLIED INFORMATICS
Language: English
Level: I
Prerequisites:
Lecturers: Paweł Szarek, PhD,Eng,
Lecture
Course: Basic
Optional
Zygmunt Meissner, PhD, Eng,
Tutorials
Hours / sem. (h)
ECTS
Workload (h)
Laboratory
60
Project
Seminar
4
120
Outcome: The students will gain knowledge and skills in various aspects of applied
informatics, valuable for a technically oriented portfolio. These skills will provide a choice
between basic programming techniques, introduction and usage of relational databases
Contents: The concept of algorithm; problem solving as one of the examples of algorithms.
Examples of coding algorithms through the use of common programming or scripting
language syntax. Comparison of compiled vs scripted languages. Examples of specialized
languages. Relational databases and SQL. Programming and data analysis techniques.
Literature:
The C Programming Language, Brian Kernighan and Dennis Ritchie
SQL in a Nutshell: A Desktop Quick Reference, K.E. Kline, D. Kline, O'Reilly and
Associates Inc. 2000
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POLISH CULTURE AND HISTORY
Language: English
Level: II
Prerequisites:
Course: Basic
Optional
Lecturers: H.Ostankowicz- Bazan, M.A. Staff: G. Balkowska,M.A., E. Belowska,M.A., A. Chwołka,M.A.,
M. Górecki, M.A., A. Hendrysiak, M.A. H. Kajetanowicz, Ph.D., J. Kozieja-Ruta, M.A., A. Paprotny,
M.A., M. Stawska, M.A., A. Zamojska, M.A.
Hours / sem. (h)
Lecture
30
Tutorials
Laboratory
Project
Seminar
ECTS
Workload (h)
T
3
90
Outcome: This course is an introduction to central issues in Polish history and culture.
Polish “Citizens” in their past lived under no less than seven different regimes. Our emphasis
in the course will be on the dialectic of continuity and change that this political history has
had influence on the Polish culture and society
Contents: Contemporary Poland cultural and historical settings are discussed. The subjects
connected with Wrocław are included. Wrocław is a city that could be seen as a metaphor of
Central Europe, Europe, or even world globalizing world as a whole. The course in Wrocław
history reflects the direction of the Polish history and culture. Introduction – general
information. Contemporary Poland. Wrocław – a city of meeting, a city that unites traditions
of the West and the East. The role Wrocław has played in Europe, has been primary
determined by its location. Polish society and everyday life in Poland. The Polish; myths,
stereotypes and paradoxes. History of Poland beginning from its orinings to the present day.
The Third Republic of Poland; the collapse of the communist government. Solidarność. The
society and its environment; social order, ethnic groups and economy. Education and culture.
Polish traditions and customs. Government and politics. Poland and its neighbors. Health
and welfare. Environment and pollution. Foreign relations and Polish Citizens living abroad.
Literature:
1. R, Bubczyk., A History of Poland in Outline, UMCS, Lublin 2006.
2. B. Suchodolski, A History of Polish Culture, Interpress, Warsaw 1986.
3. P. Wrobel., Historical dictionary of Poland : 1945-1996, Greenwood Press, 1998.
4. T.G. Ash, The Magic Lantern: The Revolution of '89 Witnessed in Warsaw, Budapest,
Berlin, and Prague. New York: Random House, 1990.
5. E. Banaszkiewicz-Zygmunt, K. Olendzki, , Poland: An Encyclopedic Guide, Polish
Scientific Publishers PWN, Warsaw 2000.
6. M.B. Biskupski, The history of Poland, Greenwood Press, 2000.
CODE
POLISH LANGUAGE FOR FOREIGNERS
Language: English
Level: II
Prerequisites:
Course: Basic
Optional
Lecturers: H. Ostankowicz- Bazan, M.A. Staff: G. Balkowska, M.A., E. Belowska, M.A., A.
Chwołka, M.A.,
M. Górecki, M.A., A. Hendrysiak, M.A. H. Kajetanowicz, Ph.D., J. Kozieja-Ruta, M.A.,
A. Paprotny, M.A., M. Stawska, M.A., A. Zamojska, M.A.
Lecture
Hours / sem. (h)
ECTS
Workload (h)
Tutorials
30
T
2
Laboratory
Project
Seminar
60
Outcome: An intensive, introductory language course for the beginning student. The goal of
the class is to work toward an active language usage through systematic conversational
practice, oral drills, listening exercises, reading and writing assignments. An introduction to
the everyday culture and traditions of Poland.
Contents: The curriculum on the elementary level A includes subjects connected mostly with
a person (personal data, education, general look, family relations, leisure time activities,
health etc.). Subsequent themes contain: the surrounding of the man (both immediate: living
place, students’ hostel, etc. and more distant: city and its institutions), every day routines,
plants, animals, weather and climate. The curriculum includes typical communicative
situations, as well. The grammatical material includes: declination of nouns, adjectives,
pronouns and numerals; verb inflexion, transitive and intransitive verbs, voices and moods of
verbs, impersonal forms of e verbs, modals and verbs connected with movement;
comparison of adjectives, noun cases and adverbs; classifying words into different parts of
speech; syntax of a simple and a compound sentence, double negation and punctuation.
Literature:
1. Burkat A., Jasińska A., Hurra!!! Po polsku 1 (A1), Kraków 2005 [CD].
2. Drwal-Straszakowa Katarzyna, Martyniuk Waldemar, Powiedz to po polsku. Say it in
Polish (A1), Kraków 2006.
3. Gałyga Danuta, Ach, ten język polski. Ćwiczenia komunikacyjne dla początkujących,
Kraków 2001 [CD].
4. Bartnicka B., Dąbkowski G., Jekiel W., Uczymy się polskiego, Warszawa 1995.
5. Burzyńska A., Anna Dąbrowska, Urszula Dobesz, Małgorzata Pasieka, Z Wrocławiem
w tle. Zadania testowe z języka polskiego dla cudzoziemców. Poziom podstawowy,
średnio/ i zaawansowany, Atut - Wrocławskie Wydaw. Oświatowe, Wrocław 2005.
6. Dąbrowska A., Burzyńska-Kamieniecka A., Dobesz U., Pasieka M., Z Wrocławiem w
tle. Zadania testowe z języka polskiego dla cudzoziemców. poziom podstawowy,
średni i zaawansowany, Wrocław 2005.
7. Lipińska E., Z polskim na ty. Podręcznik do nauczania języka polskiego dla stopnia
progowego, Kraków 2003.
8. Miodunka W., Uczymy się polskiego, [kurs video] 1996.
9. Rybicka E., Nie taki diabeł straszny. Podręcznik do nauczania słownictwa i gramatyki
dla początkujących, Kraków 1990.
10. Serafin B., Aleksandra Achtelik, Miło mi panią poznać. Język polski w sytuacjach
komunikacyjnych, Katowice 2001.
CODE
SPECTROSCOPIC METHODS IN MEDICINAL CHEMISTRY
Language: English
Course: Advanced
Year (II), semester (2)
Level: II
Obligatory
Lecturers: R Gancarz, Prof., R. Latajka, Ph.D DSc, M. Jewgiński, PhD, Ilona Dudka, MSc
Hours / sem. (h)
ECTS
Workload (h)
Lecture
30
E
3
90
Tutorials
Laboratory
Project
Seminar
30
CW
2
60
Outcome: Basic knowledge of quantum chemical foundations of spectroscopy and practical
knowledge of essential spectroscopic techniques.
Contents: Introduction to NMR spectroscopy; nucleus spin in magnetic field, chemical shift
and spin-spin coupling, 1H NMR spectroscopy, NMR spectroscopy, 1D spectra parameters,
chemical shifts and factors which have influence on them, coupling constants type H-X and
X-Y and their influence on the structure of molecules, 13C and 31P NMR spectroscopy.
Application of NMR spectroscopy in structural and conformational studies of biomolecules,
2D spectra; COSY, TOCSY, HSQC, HMBC, NOESY, ROESY. Magnetic Resonance
Imaging. Mass spectrometry; introduction, types of ionization and analyzers, connection with
GC and LC, fragmentation. Mass spectrometry; comparison of macromolecules’ method of
investigation; FAB, MALDI and ESI. IR spectroscopy; interpretation of spectra, basic
absorption bands, application in structural studies: hydrogen bonding. Introduction to UV-Vis
spectroscopy of organic compounds, monitoring of chemical reactions, electron spectroscopy
in bioinorganic chemistry and application in coordination chemistry, CD spectroscopy;
theoretical introduction, application in conformational studies of peptides and metal
complexes, EPR spectroscopy; electron spin in magnetic field, parameters of spectra,
application in studies of free radicals and metal complexes.
Literature:
1. R.M. Silverstein, F.X. Webster „Spectrometric Identification of Organic Compounds“,
J. Wiley&Sons 1996
2. H. Gunther “NMR Spectroscopy”, J. Wiley&Sons, 1994
3. J. M. Hollas, Modern Spectroscopy (Fourth Edition), Wiley & Sons, Ltd, 2004.
CODE
MOLECULAR MODELING
Language: English
Course: Advanced
Level: II
Obligatory
Prerequisites: Computational Chemistry
Lecturer: Prof.W.Andrzej Sokalski, PhD, Eng, DSc, P. Kędzierski, PhD, Eng,
E. Dyguda-Kazimierowicz. PhD, Eng
Lecture
Tutorials
Laboratory
Project
Seminar
Hours / sem. (h)
15
30
1
E
CW
ECTS
2
2
1
Workload (h)
60
60
30
Outcome: The basic understanding of computational approaches used to describe and
explain the chemical structure, its properties and structure-function relationships.
Content: The theoretical principles of molecular modeling (molecular graphics, numerical
methods, quantum chemistry, theory of intermolecular interactions, use of structural
databases, drug and catalyst design, etc.). The laboratory exercises are devoted to the
building of molecular models, their visualization and analysis. Electronic structure and
molecular property predictions, conformational analysis, molecular mechanics and dynamics
calculations, docking and modeling chemical reactions. The students’ seminar presentations
are related to successful applications of molecular modeling techniques from the recent
literature.
Literature:
1. A.R.Leach, Molecular Modelling: Principles and Applications (2nd Edition), Prentice
Hall; ISBN: 0582382106, 2001.
2. T. Schlick, Molecular Modeling and Simulation, Springer, 2002
3. L. Piela, Ideas of Quantum Chemistry, Elsevier, 2006
CODE
INSTRUMENTAL DRUG ANALYSIS
Language: English
Level: II
Prerequisites
Course: Advanced
Obligatory
Lecturers: prof. W. Żyrnicki, PhD, Eng, DSc
Staff: A. Leśniewicz, PhD, Eng, P. Pohl, PhD, Eng, B. Prusisz, PhD, Eng
Hours / sem. (h)
Exam / Course work/T: T
ECTS
Workload (h)
Lecture
15
Tutorials
Laboratory
Project
30
CW
2
60
2
60
Seminar
Outcome: An introduction to the monitoring and analysis of pharmaceutical products. Knowledge of
chemical, physical and biochemical methods used in drug analysis, with special emphasis on
spectroscopic and chromatographic techniques. Identification and quantification of organic and
inorganic species. Development of analytical skills in the area of main and trace components of
pharmaceuticals. Quality control and quality assurance.
Contents: The general problems dealing with pharmaceutical and biopharmaceutical analysis.
Analytical processes and procedures. Analytical performance. Chemical, spectroscopic,
chromatographic, biochemical, thermal and other methods. Methods of structure analysis (X-ray
diffraction among others methods). Sample preparation and separation methods. Qualitative and
quantitative analysis. Quality of analytical performance in pharmacy. Validation.
Literature:
1.
2.
3.
4.
Watson D.G., Pharmaceutical Analysis. Churchill Livingston, Edinburgh, 2005
Pharmacopeias (US, European, WHO)
Kellner R. (Ed.), Analytical Chemistry. John Wiley & Sons, London, 2004
Skoog D.A., West D.M., Holler F.J., Fundamentals of Analytical Chemistry. Saunders
College Publishing, 2003
CODE
RETRIEVAL OF SCIENTIFIC AND TECHNICAL INFORMATION
Language: English
Course: Basic
Level: II
Obligatory
Prerequisites: organic chemistry
Lecturer: prof. W.A. Sokalski, PhD, Eng, DSc
Lecture
Tutorials
Hours / sem. (h)
ECTS
Workload (h)
Laboratory
30
CW
2
Project
Seminar
60
Outcome: The critical analysis of scientific and technical information retrieved from literature and
factographic databases. Writing and editing scientific publications, CVs and grant applications.
Contents: The critical analysis techniques of information retrieved from literature (Current Contents,
Science Citation Index, etc.) and factographic (CSD, PDB, Beilstein, etc.) databases. Writing and
editing process of scientific publications, grant applications and CVs. Ethical questions in science. An
introduction to computer network services. Writing and editing scientific publications, ISI Current
Contents and Science Citation Index databases, Structural CSD and PDB databases, genetic
databases, patent databases, research grants, employment offers and fellowships. Ethical questions
in science, CVs and the Beilstein database.
Literature:
1. D. Ridley, Finding Scientific Information - Information Retrieval:, Wiley, 2002.
CODE
PRINCIPLES OF DRUG DESIGN
Language: English
Level: II
Prerequisites: organic chemistry
Course: Advanced
Obligatory
Lecturer: prof. P. Kafarski, PhD, Eng, DSc
Lecture
30
Hours / sem. (h)
ECTS
Tutorials
Laboratory
Project
Seminar
3
90
Workload (h)
Outcome: The principles governing the processes of novel drug design based on the
knowledge of both the enzymatic reaction mechanisms and the receptor 3D structures will be
presented. Useful approaches to searches and modifications of new leads will also be
presented. Moreover, non-typical means of drug design will be discussed.
Contents: How high is the cost of a new drug? Economical aspects of drug design process,
the random screening and the use of secondary metabolites as lead sources. The theory of
structural analogy, topochemical analogues of peptidic hormones, covalent and suicide
enzyme inhibitors, mechanism based on inhibitors of enzymatic reactions including the
transition-state inhibitors. Specific inhibitors for metalloenzymes including the use of
combinatorial chemistry. Non-typical enzyme inhibitors, including supramolecular inhibitors,
gene-therapy; antisense nucleotides and peptides, rybozymes, si-RNA and polyamides. The
means of designing agonists and antagonists for chosen receptors including Selex. Drug
transport through biological walls and membranes, photodynamic and other non-typical
therapies. An introduction to drug delivery techniques.
Literature:
1. P. Kafarski, B. Lejczak, Chemia bioorganiczna, PWN Waszawa 1990.
CODE
BIONANOTECHNOLOGY
Language: English
Level: II
Course: Advanced
Obligatory
Lecturer: T. Andruniów, PhD, DSc
Hours / sem. (h)
ECTS
Workload (h)
Lecture
30
E
3
Tutorials
Laboratory
Project
Seminar
15
CW
90
Outcome: The course provides basic knowledge about bionanotechnology, methods of
biomolecule design and molecular modeling utilized to design biomolecules with desired
properties.
1
30
Contents: Review of today's advanced molecular materials and physiochemical techniques
utilized to solve problems in bionanotechnology. Examples of basic capabilities of
bionanotechnology in nanomedicine, farmaceutics, design of novel biomolecular materials,
biosensors and the DNA computer. Introduction: from biotechnology to bionanotechnology.
bionanomachines, modern biomateriale, natural bionanomachinery, biomolecular structure
determination, molecular modeling, design of biomolecules to the structural principles of
bionanotechnology, Functional principles of bionanotechnology, capabilities of
bionanotechnology; nanomedicine, molecular motors, DNA computers, biosensors and
hybrid materials. The future of bionanotechnology.
Literature:
1. D. S. Goodsel: Bionanotechnology: Lessons from Nature, Wiley, 2004.
2. D. E. Reisner: Bionanotechnology, Taylor & Francis, 2006.
CODE
ADVANCED PROGRAMMING AND NUMERICAL METHODS
Language: English
Course: Advanced
Level: II
Obligatory
Prerequisites: Computer science, Programming
Lecturers: B. Szefczyk, PhD, Eng, P. Szarek, PhD, Eng, K. Strasburger, PhD., DSc
Lecture
Hours / sem. (h)
ECTS
Workload (h)
Tutorials
Laboratory
Project
Seminar
30
CW
2
60
Outcome: The learning of techniques and algorithms applied in computational chemistry,
enhancing programming skills through the use of external libraries (e.g. numerical libraries).
Contents: The topics covered by the course include problems of high-performance
computing and application of external libraries, the issue of computational complexity,
techniques of profiling, optimalization and paralellization. The students will learn basic
numerical algorithms, in addition to learning how to use the external numerical libraries. One
part of the course will be devoted to the GNU tools, including compilers and libraries.
Literature:
1. S. Teukolsky, W. Vetterling, B. Flannery, Numerical Recipes in C++ : The art of scientific
computing, William Press, 2007.
CODE
RESEARCH LABORATORY
Language: English
Level: II
Course: Basic/Advanced
Obligatory/Optional
Teaching:Traditional/Distan
ce L.
Prerequisites:
Lecturer: supervisor
Lecture
Tutorials
Hours / sem. (h)
Exam / Course
work:
ECTS
Workload (h)
Laboratory
60
Project
Seminar
T
4
120
Outcome: research work on individual project supervised by Staff members
CODE
GRADUATE SEMINAR
Language: English
Year II, semester 2
Level: II
Prerequisites:
Lecturer: Prof. W. A. Sokalski, PhD,DSc
Lecture
Tutorials
Hours / sem. (h)
Exam / Course
work:
ECTS
Workload (h)
Obligatory/Optional
ce L.
Laboratory
Project
Seminar
15
T
1
30
Outcome: Seminar presentation and discussion
Content: The aim of this course is to furnish students with practical and methodological skills to
conduct an original piece of academic research.
Literature: Academic journals and supervisor materials
CODE
QUALITY MANAGEMENT SYSTEMS
Language: English
Level: II
Prerequisites:
Course: Basic
Optional
Lecturer: R. Góra, PhD, Eng
Hours / sem. (h)
ECTS
Workload (h)
Lecture
30
T
2
60
Tutorials
Laboratory
Project
Seminar
Outcome: The main objective of the course is to introduce the fundamental concepts,
methods and techniques of quality management and conformity assessment systems, in the
field of technical operations, as well as, the current regulatory requirements in this field.
Contents: Quality management systems: introduction and historical outline. Standards of
management systems: the ISO 9000 series. Conformity assessment systems. Accreditation
as a formal recognition by an body of competence of an organization, operating within the
field of conformity assessment. The scope of PN-EN ISO/IEC 17025:2005 “General
requirements for the competence of testing and calibration laboratories.” “The accreditation
system administered by the Polish Centre for Accreditation.” Accreditation and inspection
processes over testing laboratories. International standards and guidelines in the field of
accreditation. IAF Multilateral Recognition Arrangement (IAF MLA), EA Multilateral A
agreement (EA MLA), guidelines of European cooperation for Accreditation (EA),
International Accreditation Forum (IAF) and International Laboratory Accreditation
Cooperation (ILAC). Current national regulations: (Legal Act as of 30 August 2002 regarding
the conformity assessment system, Journal of Laws No.166, Pos.1360, as an
amendment). Organization and management system. Work organization. Work and product
quality. Management system documentation, document control, review of requests, tenders
and contracts, subcontracting, purchasing services and supplies, service to the client and
complaints. Control of nonconforming work and/or irregularity from the policies and
procedures as outlined by the management system. Nonconforming testing and/or calibration
work, corrective and preventive actions, control of records, internal audits, management
reviews, the continuous improvement system. Faculty/Employees. Motivational management
techniques. Improvement of faculty/employee competence. Occupational safety and
health. Test and calibration methods and method validation. Selection of methods and their
validation. Handling of test items, sampling. Estimation of the uncertainty in measurement.
Uncertainty budget, type A and type B uncertainties. Measuring equipment and
measurement traceability. Accommodation and environmental conditions. Calibration,
reference standards and certified reference materials. Assuring the quality of test results.
Statistical process control, control charts, interlaboratory comparison and proficiency testing.
Test reports, opinions and improvements.
Literature:
1. International standard PN-EN ISO/IEC 17025:2005 “General requirements for the
competence of testing and calibration laboratories.
2. International standards PN-EN ISO 9000:2006(U) „Quality management system –
Fundamentals and vocabulary” and PN-EN ISO 9001:2001 „Quality management
systems – Requirements”;
3. International standard PN-ISO 8258:1996 „Shewhart control charts”;
4. EA-2/05 „The Scope of Accreditation and Consideration of Methods and Criteria for
the Assessment of the Scope in Testing” (identical to ILAC-G18:2002);
5. ILAC-G17:2002 „Introducing the Concept of Uncertainty of Measurement in Testing in
Association with the Application of the Standard ISO/IEC 17025”
6. ILAC-G8:1996 „Guidelines on Assessment and Reporting of Compliance with
Specification”
INTELLECTUAL PROPERTY RIGHTS AND ETHICAL QUESTIONS IN
BIOTECHNOLOGY
Language: English
Course: Basic
Level: II
Obligatory
Prerequisites:
CODE
Lecturers: L. Zurawowicz, PhD, Eng.
Hours / sem. (h)
ECTS
Workload (h)
Lecture
3
CW
2
Tutorials
Laboratory
Project
Seminar
60
Outcome: The basic
understanding
of
patent law, copyright
law,
intellectual
property
right
Literature:
differences
between
countries,
managing
R. Witek, Ethics and Patentability in Biotechnology, Science and Engineering
intellectual
property,
Ethics, 2005.
ethical
aspects
of
Singer/Stauder,
European Patent Convention, Carl Heymanns Verlag, 2003.
patenting Philip W. Grubb, Patents for Chemicals, Pharmaceuticals and Biotechnology:
biotechnological
Fundamentals of Global Law, Practice and Strategy, Oxford University Press 2005,
inventions. ISBN: 0199273782.
C. Barfield, J.E. Calfee, Biotechnology and the Patent System. Balancing Innovation and
Contents: Property Rights, AEI Press, 2007, ISBN: 978-0-8447-4256-4.
Understanding
the (Editor), The regulatory challenge of biotechnology: Human
Han Somsen
Genetics,
food and patents, Edward Elgar Publishing Limited, 2007, ISBN 978-1term
Intellectual
84542-489-3.
Property.
The
L.
Bently,
B. Sherman, Intellectual Property Law, Oxford University Press, 2008.
copyright law and the
W. Cornish, D. Llewelyn, Intellectual Property: Patents, Copyrights, Trademarks
patent
law;
basic
and Allied Rights, 6th edition, THOMSON, Sweet&Maxwell, 2007.
concepts. Intellectual
property systems in
the world. Copyrights
inCODE
science. Protecting
TERRESTRIAL ECOLOGY
the creative
Language:
Englishworks.
Course: Advanced
Year
(II), semester (3)
Level: II
Optional
Patent
law:
Prerequisites:
Physics,
Physical
Chemistry
International
and
Lecturers:
A. Chyla,
PhD,DSc
National
Patent
Agencies,
patent
Lecture
Tutorials
Project
Laboratory
procedures,
Hours / sem. (h)
30
requirements
for
T
granting
a
patent,
preparing a patent
application, types of
patents,
patent
documents
and
Seminar
ECTS
2
60
Workload (h)
Outcome: The course presents an economic system, simplified and reduced to its aspects
of energy sources and conversion and end users. A general introduction is given in physics
of radiation and spectroscopy. Practical methods, such as LIDAR or PIXE are presented
stressed extensively. Three main areas of environmental sciences are illustrated: the
greenhouse effect that keeps the Earth habitable, solar energy as a renewable energy
source, and transport physics that describe how pollutants move to places distant from their
origins. Noise, a new kind of the environmental pollution and some acoustic physics are also
presented.
Contents: Introduction to environmental sciences; economic and political points of view on
environmental issues, raw materials energy sources/conversion processes. Elementary and
environmental spectroscopy; the solar spectrum, emission spectrum of the Sun,
spectroscopy of biomolecules, spectroscopical methods in environmental analysis: LIDAR
and PIXE techniques. The energy balance in atmosphere; black body radiation and radiation
laws, a zero-dimensional greenhouse model. Terrestrial climate; elements of weather and
climate, elements of thermodynamics of atmosphere, climate modeling. Energy for human
use; nuclear energy, heat transfer, energy storage and transport, renewable energy sources.
Diffusion of pollutants; transport, flow in rivers, groundwater flow, the equations of fluid
dynamics, Gaussian plumes in the air, turbulent jets and plumes. Noise: A new
contamination of the environment? Sources; basic acoustics, human perception and noise
criteria, reducing and transmission of sound, active control of sound.
Literature:
1. Egbert Boeker i Rienk van Grondelle, Environmental physics, Wiley, Chichester, 1999
2. Clint Baird, Environmental Chemistry, W.H. Freeman and Co., New York 1995
3. Archie W. Culp Jr, Principles of Energy Conversion, McGraw-Hill, New York, 1991
CODE
DESIGN OF BIOTECHNOLOGICAL PROCESSES
Language: English
Course: Advanced
Level: II
Obligatory
Prerequisites: Biotechnology, Physical Chemistry
Lecturers: I. Polowczyk PhD, Eng., T. Kozlecki, PhD, Eng
Lecture
Hours / sem. (h)
ECTS
Tutorials
Laboratory
Project
30
T
2
Seminar
Workload (h)
60
Outcome: Understanding and practical implementation of the knowledge regarding
designing of biotechnological unit processes. Practical examples of computation, modeling,
and optimization of unit operations in biotechnological processes. The particular aims include
skills in practical usage of the basic commercial software and preparation of self made
programs for calculation of optimal process parameters, energy consumption, and costs of
processing. Optimal preparation of experiments and the utilization of experimental results.
Content: The classification and applications of the unit processes in Biotechnology. Basic
principles in designing of biotechnological processes: conservation laws, thermodynamical
laws, equilibrium, and kinetics of unit processes. Thermodynamical and rheological
properties of biofluids. Mathematical modeling of mass, heat, and momentum transport
phenomena. Solving of transport equations by means of analytical and numerical methods,
Optimal preparation of experiments and utilization of experimental results. Dimensional
analysis in experimental planning and mathematical modeling of bioprocesses. Identification
of parameters in mathematical models of bioprocesses based on experimental results.
Regression analysis, scaling up of processes and apparatuses by means of similarity theory.
Determination of similarity criteria and equations, Designing of dynamical processes. Energy
consumption and the construction of apparatus. Designing and layout of heat exchangers.
Heat conduction, convection, and radiation, boiling of liquids and condensation of vapors.
Designing diffusional processes of separation; distillation, extraction, absorption,
chromatography, adsorption, crystallization, drying and humidification. Determination of
optimal process parameters, conditions, and layout. Designing membrane processes;
microfiltration, ultrafiltration, nanofiltration and reverse osmosis. Applications of newest
membrane processes in biotechnology for recovery, purification, and concentration of
bioproducts. Membrane bioreactors. Applications of advanced diffusional processes. Affinity
separation, molecular recognition, active and facilitated transport. Separation of racemic
mixtures. Reactive membranes. Applications of hybrid systems in order to design an optimal
biotechnological process.
Literature:
1. Murray Moo Young, Comprehensive Biotechnology. Pergamon Press, Oxford.
2. J.M. Coulson and J.F. Richardson, Biochemical Engineering (in Chemical
Engineering vol. 3, chapter4), Pergamoon Press, Oxford,
3. C. O. Bennett, J. E. Myers - Momentum, Heat and Mass Transfer, Mc Graw-Hill
4. J. Welley - Fundamentals of Momentum, Heat and Mass Transfer, New York, Wiley
CODE
SELF-ORGANIZATION IN CHEMISTRY
Language: English
Level: II
Prerequisites: Physical Chemistry
Course:Advanced
Obligatory
Lecturer: prof. L. Komorowski, PhD, Eng, DSc
Hours / sem. (h)
Exam / Course work/T: T
ECTS
Workload (h)
Lecture
30
Tutorials
Laboratory
Project
Seminar
2
60
Outcome: An introduction to non-equilibrium thermodynamics; discussion of experiments
and phenomena in nature where the non-equilibrium thermodynamics is crucial. Origin of
spontaneous processes in nature, as well as, on the scientific tools. The theory of chaos and
the evolution of life are also included.
Contents: Structure and order. Motion of particles in space. Dynamical chaos. Statistical
approach to complex systems. Entropy and its applications. Elements of the linear
thermodynamics in nonequilibrium systems. Linear processes; diffusion, heat transfer,
thermoelectric phenomena, electrokinetic phenomena. General evolution principle
(Prigogine). Information and entropy. Stationary states and their stability. Kinetic modeling of
the stationary states. Hypercycles in complex systems. Evolution. Applications of kinetic
models in physics, chemistry, ecology, meteorology, hydrodynamics, astrophysics etc..
Spontaneous ordering by bifurcations. Life as a thermodynamical state of ordered systems.
Literature:
1. I. Prigogin, D. Kondepudi, Modern thermodynamics, Wiley, 1999.
CODE
GRADUATE LABORATORY
Language: English
Year II, semester 3
Level: II
Obligatory/Optional
ce L.
Prerequisites:
Lecturer: supervisor
Lecture
Hours / sem. (h)
Exam / Course
work:
ECTS
Workload (h)
CODE
Tutorials
Laboratory
225
Project
T
10
300
GRADUATE SEMINAR AND THESIS PREPARATION
Seminar
Language: English
Year II, semester 3
Level: II
Prerequisites:
Lecturer: Prof. W. A. Sokalski, PhD,DSc
Lecture
Tutorials
Hours / sem. (h)
Exam / Course
work:
ECTS
Workload (h)
Obligatory/Optional
ce L.
Laboratory
Project
Seminar
15
T
10
300
Outcome: Seminar presentation and discussion
Content: The aim of this course is to furnish students with practical and methodological skills to
conduct an original piece of academic research. Presentation will be related to MSc Thesis.
Literature: Academic journals and supervisor materials

bioinformatics_4_sem..

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