Cell Biology 2007/2008

DEPARTMENT OF CELL BIOLOGY
POZNAN UNIVERSITY OF MEDICAL SCIENCES
www.katbiolkom.ump.edu.pl
CELL BIOLOGY
2015/2016
Course Coordinator:
Professor Anna Jankowska, Ph.D.
[email protected]
Tel.: 618547190
Ass-coordinator:
Marta Kubiczak, Ph.D.
[email protected]
Tel.: 618547191
Address:
Rokietnicka 5D Street, Poznań
Fax: 618547169
Course regulation
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Transfer between groups is not possible.
Attendance at seminars and exercises is compulsory.
Being 15 minutes late for class is equal to an absence.
Eating, drinking, and having any food or beverages during classes is not allowed.
Using any electronic equipment during classes is not allowed without the permission of
TA.
Recording and taking pictures of slides during seminars is not allowed – presentations are
protected by copyright law.
Absence in class will be accepted only with a medical certificate of temporary disability
obtained from a physician or with an excuse approved by the Dean's office*.
Such excuse should be presented to the course coordinator within 2 weeks after the first
day of absence. After this time absences will not be excused.
In accordance to PUMS regulations a student may be allowed to miss no more than 10%
of classes in a given course. Therefore during Cell Biology course a student may be
absent only during one seminar (absence needs to be justified with a formal note).
In case of more than one absence, to receive the credit, student must apply to the Dean of
Faculty for permission to take a supplementary class or classes and will be charged
additionally for it, according to the fees set by the Dean’s office.
Completing the missed classes is necessary before taking the final test. Not completing
this condition before the final test precludes the student from taking the test. Such absence
as well as an unexcused absence during the final test is equal to a fail in the test.
In cases concerning procedures not included in the present Cell Biology Course
Regulations, School Regulations apply.
Quizzes
There will be an obligatory quiz concerning the covered topics in each seminar and each
exercise. Each quiz will be granted maximum 5 points. A student needs to obtain in total
at least 24 points to be allowed to take the final test. In case of getting less than 24 points
student may take an integrated test from the material covered by quizzes, which will take
place at the end of the course (2nd November 2015 at 16:30-17:30 and retake on 6th of
November 2015 at 18:00-19:00). The student is entitled to repeat this test only once.
Student has the right to see each of his/her written papers or answer sheet within 5
working days following the announcement of the results.
*On the condition that the absence is excused, students who were absent in class, they
may take the missed quiz on 2nd November 2015 at 16:30-17:30.
List of topics to be covered in the quiz can be found at:
http://www.katbiolkom.ump.edu.pl/dydaktyka_en.htm
or
http://pums.ump.edu.pl/programs/6-year-m-d-program/curriculum-overview-for-the-6year-m-d-program/
Final test
There will be a written examination at the end of the course on 18th of November at
15:15-16:30 pm at Examination room, Parkowa 2.
Using any electronic equipment during the test is not allowed!!!
The test will consist of 30 multiple choice questions. It will cover problems from both
seminars and the exercises. To get credit from the test, 60% of questions must be
answered correctly.
There will be two retakes of the final test.
Retake I: 25th of November 2015 at 15:15 – 16:30 pm at Examination room, Parkowa 2.
Retake II: 2rd of December 2015 at 15:15 to 16:30 pm at Examination room, Parkowa 2.
Credit
To get credit from Cell Biology attendance on the seminars and exercises as well as
passing quizzes and the final test are obligatory.
Final grades classification
Course grades will be calculated based on final test scores.
-
very good (5.0)
- 90% and more
better than good (4.5) - ≥ 85%
good (4.0)
- ≥ 80%
fairly good (3.5)
- ≥ 75%
satisfactory (3.0)
- ≥ 66%
unsatisfactory (2.0)
- <60%, failed
Exemptions
An exemption allows students, who completed Cell Biology at university level, to be absent at
the seminaries and exercises.
Taking the final test is still obligatory.
Completing the course is essential to be able to take NBME exam.
Recommended books:
1. Bruce Alberts, D. Bray, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter: Essential
Cell Biology. An introduction to the Molecular Biology of the Cell; Gerland Publishing,
Inc, London & New York 1998 – elementary book
2. Nalini Chandar, Susan Viselli: Cell and Molecular Biology; Lippincott Williams &
Wilkins 2010 – for the review
Cell Biology 2015/2016
SEMINARIES
Place:
R – 5D Rokietnicka St.;
24 – room No 24, Eskulap, Marcelińska St.;
25 – room No 25, Eskulap, Marcelińska St.;
106 – room No 106, Collegium Chmiela, 4 Swiecickiego St.;
107 – room No 107, Collegium Chmiela, 4 Swiecickiego St.;
211 – room No 211, Collegium Stomatologicum, 70 Bukowska St.;
212 – room No 212, Collegium Stomatologicum, 70 Bukowska St.;
404 – room No 404, Collegium Wrzoska, 79 Dabrowskiego St.;
407 – room No 407, Collegium Wrzoska, 79 Dabrowskiego St.;
413 – room No 413, Collegium Wrzoska, 79 Dabrowskiego St.;
Recording and taking the pictures of slides during seminaries is not allowed. The
presentations are protected by copyright law.
Seminar 1
Cell organization and dynamics. Prof. Anna Jankowska, Ph.D.; 2x45
Topics to be covered in the quiz: compartmentalization of Eukaryotic cell; organelles and their
major functions; types of cytoskeleton filaments; basic structure of biological membranes; plasma
membrane components.
Seminar 2
Principles of membrane transport. Cell signalling. Prof. Anna Jankowska, Ph.D.; 2x45
Topics to be covered in the quiz: basic structure of biological membranes; selective permeability
of plasma membrane, paracrine vs. endocrine signaling; signaling molecules; types of receptors
(intracellular receptors, membrane bound receptors classes); G proteins; second messengers.
Seminar 3
Structure and function of cell nucleus. The flow of genetic information. Bioenergetics and
metabolism: Mitochondria and Peroxisomes. Marta Kubiczak M.Sc.; 2x45min
Topics to be covered in the quiz: DNA and RNA structure; types of RNA and their function DNA
packing; basis of replication, transcription and translation; structure and function of
mitochondria.
Seminar 4
Intracellular compartments and vesicular traffic in the secretory and endocyting pathways (endoand exocytosis). Aleksandra Śliwa, Ph.D.; 2x45min
Topics to be covered in the quiz: ribosomes structure and function; smooth and rough
endoplasmic reticulum – structure and function; Golgi complex; lysosomes.
Seminar 5
The cell cycle. Abnormal cell growth. Cell death. Maria Wołuń-Cholewa, Ph.D.; 2x45min
Topics to be covered in the quiz: cell cycle stages, interphase phases; mitosis, meiosis.
EXERCISES
Place: Laboratories of Cell Biology Department, 5D Rokietnicka Street
Drinking or eating in the lab is not allowed.
Labcoats and printed handouts are obligatory.
Exercises 1
Cell culture. Marta Kubiczak Ph.D./ Paulina Urbaniak, M.Sc; 150 min
Isolation and fractionation of cells and primary culture.
Maintenance of the culture-cell lines.
Three-dimensional culture systems, organs’ culture.
Topics to be covered in the quiz: cell organelles and their function; cell cycle stages, interphase
phases.
Exercises 2
Antigen-antibody reaction and its clinical application. Paulina Urbaniak, M.Sc/ Izabela Skibinska
Ph.D.; 150 min
The functional properties and structure of antibodies.
Immunological methods: immunohistochemistry, ELISA, cytometry.
Over the counter tests.
Topics to be covered in the quiz: cell organelles and their function, innate and adaptive immune
system, antigen, antibodies, principles of ELISA methods.
Exercises 3
Analysis of nucleic acids. Aleksandra Śliwa, Ph.D/Piotr Białas M.Sc; 150 min
Quantitative and qualitative assessment of nucleic acids.
Restriction Fragment Length Polymorphism – the use of restriction enzymes in medical
diagnostic
Topics to be covered in the quiz: cell organelles and their function, DNA structure, sources of
DNA for its analysis, DNA packing, restriction enzymes, RFLP method.
Cell Biology 2015/2016
TIME TABLE – SEMINARS/EXERCISES
Sem – seminars; Ex- exersices;
S1-S5 – Seminar Group; A-Ł – Exercise Group
Places:
R – 5D Rokietnicka St.;
23 – room No 23, Eskulap, Marcelińska St.;
24 – room No 24, Eskulap, Marcelińska St.;
25 – room No 25, Eskulap, Marcelińska St.;
106 – room No 106, Collegium Chmiela, 4 Swiecickiego St.;
107 – room No 107, Collegium Chmiela, 4 Swiecickiego St.;
210 – room No 210; Collegium Stomatologicum, 70 Bukowska St.;
211 – room No 211, Collegium Stomatologicum, 70 Bukowska St.;
212 – room No 212, Collegium Stomatologicum, 70 Bukowska St.;
307– room No 307, Collegium Stomatologicum, 70 Bukowska St.;
404 – room No 404, Collegium Wrzoska, 79 Dabrowskiego St.;
407 – room No 407, Collegium Wrzoska, 79 Dabrowskiego St.;
413 – room No 413, Collegium Wrzoska, 79 Dabrowskiego St.;
Sem1- Anna Jankowska, Ph.D.
Sem2- Anna Jankowska, Ph.D
Sem3- Marta Kubiczak, Ph.D
Sem4- Aleksandra Głodek, Ph.D.
Sem5- Maria Wołuń-Cholewa, Ph.D.
weeks
09/28
10/02
Monday
14:00-15:30
Sem1/S3/R
Sem3/S4/210
Sem4/S5/212
Sem5/S2/407
Ex.1- Marta Kubiczak , Ph.D
Ex.2- Paulina Urbaniak, M.Sc.,Izabela Skibińska , Ph.D
Ex.3- Aleksandra Głodek, Ph.D/Piotr Białas M.Sc
Tuesday
Wednesday
Thursday
17:45-19:15
Sem4/S2/R
Sem5/S5/106
Sem3/S3/107
15:15-16:45
Sem3/S1/404
Sem5/S3/413
Sem1/S4/211
12:00-13:30
Sem1/S5/R
17:45-19:15
Sem2/S2/R
Sem5/S5/212
15:15-16:45
Sem2/S3/R
Sem4/S4/212
12:00-13:30
Sem4/S3/23
Sem5/S1/25
Sem3/S2/307
Friday
9:30-11;00
Sem2/S5/R
16:45-18:15
Sem1/S2/R
Sem4/S1/210
16:00-17:30
Sem1/S1/R
10/0510/09
INAUGURATION
DAY
16:45-18:15
Sem2/S4/R
10/1210/16
12:30-15:00
Ex.1 K
Ex.2 I
Ex.3 L
12:00-13:30
Sem5/S4/210
Sem3/S5/24
16:00-17:30
Sem2/S1/ R
8:00-10:30
Ex.1 B
Ex.2 C
Ex.3 A
15:45-18:15
Ex.1 Ł
Ex.2 G
Ex.3 H
11:45-14:15
Ex.1 M
Ex.3 Ł
15:45-18:15
Ex.1 D
Ex.2 E
Ex.3 F
8:00-10:30
Ex.1 A
Ex.2 B
Ex.3 C
15:15-17:45
Ex.1 H
Ex.2 F
Ex.3 J
17:00-19:30
Ex.1 E
Ex.2 A
Ex.3 D
15:45-18:15
Ex.1 C
Ex.2 D
Ex.3 B
15:45-18:15
Ex.1 G
Ex.2 H
Ex.3 M
10/1910/23
11:30-14:00
Ex.1 I
Ex.2 J
Ex.3 K
weeks
10/2610/30
Monday
12:00-14:30
Ex.1 J
Ex.2 K
Tuesday
17:30-20:00
Ex.2 M
Ex.3 G
Wednesday
Thursday
Friday
15:15-17:45
Ex.1 F
Ex.2 L
Ex.3 I
15:30-18:00
Ex.1 L
Ex 2 Ł
Ex.3 E
11/0211/06
16:30-17:30
Integrated test from
quizzes
18:00-19:00
Retake of test from
quizzes
11/0911/13
11/1611/20
11/2311/27
11/30
12/04
18.11.2015
Final exam
15:15-16:30
Examination room,
2 Parkowa St.
25.11.2015
RETAKE I of final exam
15:15-16:30
Examination room,
2 Parkowa St.
2.12.2015
RETAKE II of final
exam
15:15-16:30
Examination room,
2 Parkowa St.