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VOL. 211 Review Retigabine: the newer potential antiepileptic drug. Piotr Czuczwar, Agnieszka Wojtak, Anna Cioczek- Czuczwar, Jolanta Parada-Turska, Ryszard Maciejewski, Stanis³aw J. Czuczwar 220 Review Guillain-Barré syndrome (GBS). Anand B. Pithadia, Nimisha Kakadia 233 Review COX-2 as a target for cancer chemotherapy. Nilanjan Ghosh, Rituparna Chaki, Vivekananda Mandal, Subhash C. Mandal 245 Effect of acute and chronic treatment with QCF-3 (4-benzylpiperazin-1-yl) (quinoxalin-2-yl) methanone, a novel 5-HT! receptor antagonist, in animal models of depression. Thangaraj Devadoss, Dilip K. Pandey, Radhakrishnan Mahesh, Shushil K. Yadav 258 Buspirone improves 6-hydroxydopamine-induced catalepsy through stimulation of nigral 5-HT) receptors in rats. Alireza M. Nayebi, Siyamak R. Rad, Mehdi Saberian, Saeid Azimzadeh, Morteza Samini 265 Pregnenolone sulfate infused in lateral septum of male rats impairs novel object recognition memory. Federico Nanfaro, Ricardo Cabrera, Vanesa Bazzocchini, Myrian Laconi, Roberto Yunes 273 Evaluation of the anticonvulsant activity of 6-(4-chlorophenyoxy)-tetrazolo[5,1-a]phthalazine in various experimental seizure models in mice. Xian-Yu Sun, Cheng-Xi Wei, Xian-Qing Deng, Zhi-Gang Sun, Zhe-Shan Quan 278 Pharmaco-EEG-based assessment of the interaction between ethanol and oxcarbazepine. Bogus³awa Pietrzak, El¿bieta Czarnecka 287 Anti-inflammatory plasma cytokines in children and adolescents with migraine headaches. Leszek Boækowski, Joanna migielska-Kuzia, Wojciech Sobaniec, Beata ¯elazowska-Rutkowska, Wojciech Ku³ak, Krzysztof Sendrowski 292 Analysis of the excitatory motor response evoked by nicotinic and muscarinic blockade of ovine small bowel. Krzysztof W. Romañski 304 Effects of aspirin on the levels of hydrogen sulfide and sulfane sulfur in mouse tissues. Anna Bilska, Ma³gorzata Iciek, Inga Kwiecieñ, Karol Kaniecki, Magdalena Paliborek, Eugeniusz Somogyi, Joanna Piotrowska, Bogdan Wiliñski, Marta Góralska, Zbigniew Srebro, Lidia W³odek 311 Aldosterone augments LOX-1-mediated low-density lipoprotein uptake in human umbilical artery endothelial cells. Ashraf Taye, Tatsuya Sawamura, Henning Morawietz 319 Anticancer activity of newly synthesized azaphenothiazines from NCIs anticancer screening bank. Krystian Pluta, Ma³gorzata Jeleñ, Beata Morak-M³odawska, Micha³ Zimecki, Jolanta Artym, Maja Kociêba 62 NUMBER 2 2010 333 Modulation of P-glycoprotein activity by the substituted quinoxalinone compound QA3 in adriamycinresistant K562/A02 cells. Li-Rui Sun, Julia Li Zhong, Shu-Xiang Cui, Xun Li, Stephen Geoffrey Ward, Yan-Qiu Shi, Xiao-Fan Zhang, Yan-Na Cheng, Jian-Jun Gao, Xian-Jun Qu 343 Effect of simvastatin on nitric oxide synthases (eNOS, iNOS) and arginine and its derivatives (ADMA, SDMA) in ischemia/reperfusion injury in rat liver. Ma³gorzata Trocha, Anna Merwid-L¹d, Andrzej Szuba, Ewa Chlebda, Ma³gorzata Pieniewska, Tomasz Sozañski, Adam Szel¹g 352 Selenitetriglicerydes affect CYP1A1 and QR activity by involvement of reactive oxygen species and Nrf2 transcription factor. Piotr Suchocki, Irena Misiewicz-Krzemiñska, Katarzyna Skupiñska, Katarzyna Niedwiecka, Katarzyna Lubelska, Zbigniew Fija³ek, Teresa Kasprzycka-Guttman 362 Activities of biotransformation enzymes and flubendazole metabolism in lambs (Ovis aries): effect of gender and flubendazole therapy. Hana Bártíková, Veronika Køíová, Martina tìpnièková, Jiøí Lamka, Vladimír Kubíèek, Lenka Skálová, Barbora Szotáková 374 Residual fraction of the area under the curve as a qualitative criterion in pharmacokinetic studies. Tomasz Grabowski, Jerzy J. Jaroszewski, Piotr Jakubowski SHORT COMMUNICATIONS 383 Effects of sildenafil on pentylenetetrazol-induced convulsions in mice and amygdala-kindled seizures in rats. Dorota Nieoczym, Katarzyna Soca³a, Chris Rundfeldt, Piotr Wla 392 Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models. Katarzyna Soca³a, Dorota Nieoczym, Chris Rundfeldt, Piotr Wla 398 Carbamazepine intoxication in alcohol dependent epileptic patients. Wojciech Piekoszewski, Ewa Florek, Dorota Szpak, Lucyna Kramer, Wojciech Jawieñ 405 Early co-administration of vitamin E acetate and methylcobalamin improves thermal hyperalgesia and motor nerve conduction velocity following sciatic nerve crush injury in rats. Aashish S. Morani, Subhash L. Bodhankar 410 Antiplatelet effect of statins is augmented in diabetic rabbits. Ivan Kociæ, Beata Racek-Król, Iga Wapniarska, Izabela Rusiecka, Robert Wasilewski, Marcin Bitel 414 Synthesis and cytotoxic activity of G3 PAMAM-NH dendrimer-modified digoxin and proscillaridin A conjugates in breast cancer cells. Katarzyna Winnicka, Krzysztof Bielawski, Anna Bielawska 427 Abstracts of the Third Conference on PROGRESS IN EPILEPTIC AND ANTIEPILEPTIC DRUGS 447 Note to Contributors