مقایسه‌ی سروپروالانس هلیکوباکترپیلوری در بیماران دچار آکنه‌ی رُزاس

مقایسه‌ی سروپروالانس هلیکوباکترپیلوری در بیماران دچار آکنه‌ی رُزاس

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76
Comparison of Helicobacter Pylori Seroprevalance between Acne Rosacea and Healthy Group
Mobaien AR1, Zamanian A2, Farshchian M3, Ansar A3, Yazdanfar A3
1
Dept. of Infectious Diseases, Zanjan University of Medicine Science, Zanjan, Iran
2
Dept. of Dermatology, Iran University of Medical Sciences, Tehran, Iran
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3
Dept. of Dermatology, Hamadan University of Medical Science, Hamadan, Iran
Corresponding Author: Mobaien AR, Dept. of Infectious Diseases, Zanjan University of Medical Science, Zanjan,
Iran
E-mail: [email protected]
Received: 23 Aug 2009
Accepted: 12 Apr 2010
Background and Objective: Acne rosacea is a chronic skin disease with unknown etiology. Some reports
have suggested an increased prevalence of helicobacter (H) pylori infection in patients with acne rosacea but
it is controversial. This study was designed to compare the prevalence of H pylori between the acne rosacea
patients and the healthy control group.
Materials and Methods: This case-control study was performed on 30 patients with acne rosacea and 60
healthy individuals as a control group. 5 mL blood was taken from each person and anti-H pylori IgG was
measured by enzyme-linked immunosorbent assay.
Results: Mean age was 45.8±14.05 years in acne rosacea patients and 41.4±12.3 years in control group.
Seventeen (56.7%) ofpatients and fifty two (86.2%) of controls were infected by H pylori (P=0.002), but
mean serum anti-H pylori IgG level was significantly higher in acne rosacea patients comparing to healthy
control group (139.49±174.15 g/mL vs 38.87±23.50, P=0.005).
Conclusion: Despite increased mean serum anti-H pylori IgG levels in acne rosacea patients, H pylori was
more prevalent in healthy control group, in this study.
Keywords: Acne rosacea, Helicobacter pylori, Anti-H pylori IgG
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