Session 1 EPR in Biophysics Session 2 Biophysics of oxidative stress

Session 1 EPR in Biophysics Session 2 Biophysics of oxidative stress

TUESDAY, 10 FEBRUARY 2015
10:00
9:00-14:00
13:00-14:00
14:00-14:05
Departure to Zakopane; Faculty of BBB, Gronostajowa Street
Session 1
EPR in Biophysics
14:05-14:15
Opening of the session
Riccardo Basosi, Department of Biotechnology, Chemistry and Pharmacy, University
of Siena, Siena, Italy; “ENERGY: from the Principles of Thermodynamics to Horizon
14:15-14:45
Registration
Lunch
Opening of the XLII Winter School
2020”
Howard J. Halpern, Department Of Radiation & Cellular Oncology, Division Of The
14:45-15:15
15:15-15:45
15:45-16:10
16:10-16:25
16:25-16:35
Biological Sciences And The Pritzker School Of Medicine, University Of Chicago,
Chicago, USA; “Anatomic localization & treatment response from quantitative images
of tissue pO2, pH and redox balance with EPR imaging”
Wojciech Froncisz, Faculty of Biochemistry, Biophysics and Biotechnology,
Jagiellonian University, Krakow, Poland; “The impact of loop-gap structures on
biophysics and friendship”
Artur Osyczka, Department of Molecular Biophysics, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “Detection of
semiquinone intermediate state at the quinol oxidation site of cytochrome bc1 by
EPR”.
Marcin Sarewicz, Department of Molecular Biophysics Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “Studying role
of motion of Fe-S head domain in catalysis and reactive oxygen species generation by
cytochrome bc1”
Rafal Pietras, Department of Molecular Biophysics Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; „Application of
distance-dependent pulse EPR measurements to investigate protein-protein
interactions in cytochrome c2 – cytochrome bc1 system”
16:35-16:50
COFFEE BREAK
Session 2
Biophysics of oxidative stress
16:50-17:00
17:00-17:30
17:30-18:00
18:00-18:30
18:30-19:00
19:00-19:30
19:30-19:40
19:40-19:50
19:50-20:00
20:00
Opening of the session
Claudine Kieda, Molecular Biophysics Centre, Orléans, France; “Tumor hypoxia
compensation to normalize vascularization by ROS production”
Balaraman Kalyanaraman, Medical College of Wisconsin, Milwaukee, Wisconsin,
USA; “High throughput screening of a library of FDA-approved chemicals as inhibitors
of NADPH oxidase and pancreatic cancer”
Grzegorz Bartosz, Department of Biochemistry and Cell Biology, University of
Rzeszow, and Department of Molecular Biophysics, University of Lodz, Poland; “Does
anticancer agent 3-bromopyruvate act via oxidative stress?”
Luigi Zecca, Institute of Biomedical Technologies, National Research Council of Italy,
Segrate, Milan, Italy; “Neoromelanins, oxidative stress and Parkinson`s disease”
Tadeusz Sarna, Department of Biophysics, Faculty of Biochemistry, Biophysics and
Biotechnology, Jagiellonian University, Krakow, Poland; “Oxidative stress mediated by
photosensitized oxidation reactions”
Anna Pilat, Department of Biophysics, Faculty of Biochemistry, Biophysics and
Biotechnology, Jagiellonian University, Krakow, Poland; “Expression of heme
oxygenase-1 in retinal pigment epithelium cells containing phagocytized melanosomes
subjected to sublethal oxidative stress”
Anna Pawlak, Department of Biophysics, Faculty of Biochemistry, Biophysics and
Biotechnology, Jagiellonian University, Krakow, Poland; “Photoreactivity of human
retinal lipid extracts increases with age of donors”
Andrzej Zadlo, Department of Biophysics, Faculty of Biochemistry, Biophysics and
Biotechnology, Jagiellonian University, Krakow, Poland; “The effect of selected
transition metal ions on physicochemical properties of melanin”
Welcome party and reminiscences
WEDNESDAY, 11 FEBRUARY 2015
8:30-9:30
9:30-13:00
13:00-14:00
Breakfast
Free time/Trip to Koscieliska Valley
Lunch
Session 1
Genetic alterations and phenotypic effects
14:00-14:30
14:30-15:00
15:00-15:30
15:30-16:00
16:00-16:15
16:15-16:45
Rafal Ploski, Department of Medical Genetics, Warsaw Medical University, Warsaw,
Poland; “Massive parallel sequencing technology – the whole exome sequencing”
Manfred Kayser, Department of Forensic Molecular Biology, Erasmus University
Medical Center Rotterdam, Rotterdam, Netherlands; “From genome-wide association
to molecular function: transcriptional regulation of human pigmentation genes”
Wojciech Branicki, Department of General Biochemistry, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “Forensic DNA
phenotyping – prediction of human appearance from DNA variants”.
Sanja Kezic, Academic Medical Center, Coronel Institute, Amsterdam, Netherlands;
“The role of genetic and environmental factors for the expression of epidermal protein
filaggrin”
Ewelina Pospiech, Faculty of Biology and Earth Sciences, Jagiellonian University,
Krakow, Poland; “Variants of SCARB1 and VDR may be associated with increased risk
of clear cell renal cell carcinoma”
Anna Wasowska, GENOMED Company; “How Next Generation Sequencing (NGS)
can improve your research“
16:45-17:00
COFFEE BREAK
Session 2
Structure prediction and function
17:00-17:15
17:15-17:45
17:45-18:15
18:15-18:45
18:45-19:00
19:00-19:15
19:15-19:30
19:30-19:45
19:45
Roche Company presentation
Jerzy Dobrucki, Laboratory of Cellular Biophysics, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “Superresolution (sub-diffraction) optical microscopy and its applications in studies of
structure of the cell nucleus, and DNA damage and repair”
Grzegorz Dubin, Department of Microbiology, Faculty of Biochemistry, Biophysics
and Biotechnology and Malopolska Centre for Biotechnology, Jagiellonian University,
Krakow, Poland; “Development of MDM2/MDMX-p53 interaction inhibitors”
Anna Wisniewska-Becker, Department of Biophysics, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University; “EPR studies on properties of
model photoreceptor membranes”
Andrzej Gorecki, Department of Physical Biochemistry, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “Transcription
factors – the dynamic elements in the gene expression process”
Piotr Stepien, Department of Biophysics and Department of Physical Biochemistry,
Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University,
Krakow, Poland; “Comparative EPR studies on lipid bilayer properties in nanodiscs and
liposomes”
Justyna Karkowska-Kuleta, Department of Analytical Biochemistry, Faculty of
Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland;
“Cell wall proteome of pathogenic fungi”
Natalia Stach, Department of Microbiology and Department of Analytical
Biochemistry, Faculty of Biochemistry Biophysics and Biotechnology, Jagiellonian
University; “Unique substrate specificity of SplE serine protease of Staphylococcus
aureus”
Poster session 1
THURSDAY, 12 FEBRUARY 2015
8:30-9:30
9:30-12:00
13:00-14:00
Breakfast
Ski competition
Lunch
Session 1
Regulatory molecules
14:00-14:30
14:30-15:00
15:00-15:30
15:30-15:45
15:45-16:00
16:00-16:15
16:15-16:30
Zofia Szweykowska-Kulinska, Department of Gene Expression, Institute of
Molecular Biology and Biotechnology, Faculty of Biology, Poznan, Poland; “The
crosstalk between splicing and microRNA processing machineries in the biogenesis of
miRNAs”
Ewa Zuba-Surma, Department of Cell Biology Faculty of Biochemistry, Biophysics
and Biotechnology, Jagiellonian University, Krakow, Poland; “Stem cells - derived
microvesicles as mediators of cell-to-cell communication - potential applications in
regeneration”
Benedykt Wladyka, Department of Analytical Biochemistry, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “Proteomic
approach in a search for virulence factors from poultry-originated Staphylococcus
aureus strains”
Sylwia Bobis-Wozowicz, Department of Cell Biology, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “Utility of
microvesicles derived from mesenchymal stem cells in transporting DNA modifying
enzymes for genome engineering”
Elzbieta Boratyn, Laboratory of Molecular Genetics and Virology, Faculty of
Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland;
“The Effects of Regnase-1 Enforced Expression in Human Neuroblastoma”
Monika Rak, Department of Cell Biology, Faculty of Biochemistry, Biophysics and
Biotechnology, Jagiellonian University, Krakow, Poland; “Cationic polyprenyl
derivatives as efficient DNA and RNA vehicles”
Janusz Ligeza, Department of General Biochemistry, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “The role of
MCPIP1 in clear cell renal carcinoma”
16:30-17:00
COFFEE BREAK
Session 2
Cross-talk of signaling pathways
Halina Gabrys, Department of Plant Biotechnology, Faculty of Biochemistry,
17:00-17:30
17:30-18:00
18:00-18:30
18:30-18:45
18:45-19:00
19:00-19:15
19:30
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “Blue light
signaling in plants”
Alicja Jozkowicz, Department of Medical Biotechnology, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “Stressful way
to maturation: HO-1 in rhabdomyosarcoma”
Tomasz Sarnowski, Department of Protein Biosynthesis, Institute of Biochemistry
and Biophysics Polish Academy of Sciences, Warsaw, Poland; “Global control of
eukaryotic gene expression depends on chromatin remodeling by SWI/SNF complexes”
Irena Horwacik, Laboratory of Molecular Genetics and Virology, Faculty of
Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland;
“Cytotoxic properties of a 14G2a monoclonal antibody binding to GD2 ganglioside”
Malgorzata Durbas, Laboratory of Molecular Genetics and Virology, Faculty of
Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland;
“Delineation of a PI3K/Akt/mTOR pathway downregulation in intracellular signaling of
GD2 ganglioside-targeted neuroblastoma”
Szymon Czauderna, Department of Medical Biotechnology, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “ApoE
polymorphism influence macrophage polarization and microRNA expression profile”
Poster session 2
FRIDAY, 13 FEBRUARY 2015
8:30-9:30
9:30-13:00
13:00-14:00
Breakfast
Free time/Trip to Kondratowa Valley
Lunch
Session 1
Cell and microenvironment
Marta Miaczynska, International Institute of Molecular and Cell Biology, Warsaw,
14:00-14:30
Poland; “ESCRT-ing NF-κB: The ESCRT activity limits basal NF-κB signaling”
Joanna Koziel, Department of Microbiology, Faculty of Biochemistry, Biophysics and
14:30-15:00
15:00-15:30
15:30-15:45
15:45-16:00
16:00-16:15
Biotechnology, Jagiellonian University, Krakow, Poland; Uptake of apoptotic
granulocytes promotes the escape of intracellular Staphylococcus aureus from
macrophages leading to dissemination of infection
Krzysztof Pyrc, Department of Microbiology, Faculty of Biochemistry, Biophysics and
Biotechnology, Jagiellonian University, Krakow, Poland; “Coronavirinae: the early
stages of infection”
Monika Zukowska, Department of Medical Biotechnology, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “HO-1
deficiency accelerates aging of hematopoietic stem cells”
Agata Szade, Department of Medical Biotechnology, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “New strategy
to mobilize bone marrow cells to the blood: unexpected application of cobalt
protoporphyrin IX”
Maciej Ciesla, Department of Medical Biotechnology, Faculty of Biochemistry,
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; “Valproic acid:
epigenetic modifier of rhabdomyosarcoma development”
16:15-16:45
COFFEE BREAK
Session 2
Progress in therapy
Jan Barciszewski, Institute of Bioorganic Chemistry, Polish Academy of Sciences,
16:45-17:15
Poznan, Poland; “RNA gymnastics. From bench to bedside”
Jozef Dulak, Department of Medical Biotechnology, Faculty of Biochemistry,
17:15-17:45
17:45-18:15
18:15-18:30
Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland; Adult stem
cells: hopes and hypes of regenerative medicine
Martyna Elas, Department of Biophysics, Faculty of Biochemistry, Biophysics and
Biotechnology, Jagiellonian University, Krakow, Poland; DNA damage and migration of
melanoma cells irradiated with proton beam and X-rays
Anna Grochot-Przeczek, Faculty of Biochemistry, Biophysics and Biotechnology,
Jagiellonian University, Krakow, Poland; “Novel engineered fusion molecule overcomes
TRAIL-resistance and forcefully inhibits tumor growth via Mdm2-p53 dependent
pathway”
19:00
Cocktail party
SATURDAY, 14 FEBRUARY 2015
8:30-9:30
10:00
Breakfast
Departure to Krakow