docſŹźŝ ƾ šřźŧř ƵŹŚƈƗ į ŝō ƾģŹřŵǀƲ źŝ ŚƷźŤƯřŹŚě ƽŝǀƃƺǀưǀŚ ƾƿ
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ſŹźŝ ƾ šřźŧř ƵŹŚƈƗ į ŝō ƾģŹřŵǀƲ źŝ ŚƷźŤƯřŹŚě ƽŝǀƃƺǀưǀŚ ƾƿ
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National, LJ. regional, and global trends in fasting plasma ischaemic stroke.Lancet Neurol. 2012;11: 261-71. glucose and diabetes prevalence since 1980: 7- Grant RW, Kirkman MS. Trends in the systematic analysis of health examination surveys evidence level for the American Diabetes and epidemiological studies with 370 country- Association’s “Standards of Medical Care in years and 2.7 million participants. Lancet. 2011; Diabetes” from 2005 to 2014. Diabetes Care. 378: 31-40. 2015; 38: 6-8. 2- Saberi M, Gholami S. An investigation on the 8- Anderson RA, Broadburst CL, Polansky MM, effects of the Aloe Vera extract on the thickness et al. Isolation and characterization of polyphenol of the retina in male diabetic rats. Iran J Veter type A polymers from cinnamon with Insulin-like Res. 2012; 13: 41-48. biological activity. J Agric Food Chem. 2004; 52: 3- Poitout V. Glucolipotoxicity of the pancreatic 65-70. beta-cell: myth or reality? Biochem Soc Trans. 9- Ali MK, Bullard KM, Saaddine JB, Cowie CC, 2008; 36: 901-4. Imperatore G, Gregg EW. Achievement of goals 4- Yoon JW, Jun HS. Cellular and molecular roles in U.S. diabetes care, 1999-2010. N Engl J Med. of beta cell autoantigens, macrophages and T cells 2013; 368: 1613-24. in the pat hogenesis of autoimmune diabetes. Arch 10- Khan A, Sfdar M, Ali Khan MM, Khattak Pharm Res. 1999; 22: 437-47. KN, Anderson RA. Cinnamon improves glucose 5- Kahn BB, Flier JS. Obesity and insulin and lipids of people with type 2 diabetes. Diabetes resistance. J Clin Invest. 2000; 106 : 473-81. Care. 2003; 26: 3215-8. Diabetes, hyperglycaemia, and acute æèîéŶƴƠſřƹƲưƸŝæåæƽƵŹŚưƃ çèƽƵŹ ƹŵƱŚºŬƳŻƾƳŚƯŹŵƾŤƃřŶƸŝšŚƯŶųƹƾĪƃżěƭƺƬƗƵŚĮƄƳřŵƾƄƷƹĦěƾưƬƗƽ ƶƬŬƯ Downloaded from zums.ac.ir at 11:18 IRST on Wednesday March 8th 2017 źƳƽŚƷšŹ ŹŵƱƺųƭźſƾƿŚǀưǀƃƺǀŝƽŚƷźŤƯřŹŚěźŝƲǀģŹřŵƾŝōįƵŹŚƈƗ šřźŧřƾſŹźŝ 11- Shah AH, AL-Shareef AH, Ageel AM, 18- Varalakshmi, Vijayaananand A, Karpagm T, Qureshi S. Toxicity studies in mice of common Sugunabai J: In vitro antimicrobial and anticancer spices Cinnamomum zeylanicum bark and piper activity of Cinnamommum Zeylaicum Linn bark longum fruits. Plant Food Hum Nut. 1998; 52: extracts. Int J Pharm Pharmaceut Sci. 2014; 6: 231-9. 12-18. 12- Gurdip S, Maurya MP, Cesar AN, Catalan A. 19- Arabi S, Arshami J, Haghparast AR. Effects Comparision and of Salvia Officinalis L. Extract on Biochemical antimicrobial studies of cinnamon leaf and bark Blood Parameters in Male Rats J Zanjan Unive volatile oil. Food Chem Toxicol. 2007; 45: 1650- Med Sci. 2014; 22: 34-42. 61. 20- Aslani E, Naghsh N, Ranjbar M. Cytotoxic 13- Sang B, Wolters M, Schmitt B, et al. Effect of effects of aqueous and alcoholic extracts of cinnamon extract on plasma glugose, HbA1c and Mentha spicata leaves on K562 cell line. J Zanjan serum lipid in diabetes mellitus type 2. Eur J Clin Unive Med Sci. 2014; 95: 67-79. Invest. 2006; 36: 340-4. 21- Shariatzadeh SMA, Hamta A, Soleimani M, 14- Braun L, Cohen M. Herbs and supplement an Darvishi S. Comparison of the cytotoxicity of evidence-based guide, sydney. 2th ed. New York: aqueous and ethanolic extracts of saffron (Crocus Elsevier Mosby publishers. 2005; 808. sativus L) with paclitaxel as a chemotherapy drug 15- Kumar M, Prasad SK, Krishnamurthy S, in breast cancer cell line (4T1). J Zanjan Unive Hemalatha S. Antihyperglycemic activity of Med Sci. 2014; 94: 83-95. Houttuynia cordata Thunb. in streptozotocin- 22- induced diabetic rats. Adv Pharmacol Sci. 2014; Cytotoxicity and antimicrobial activity of Salvia 20-32. officinalis L. flowers. Sudan JMS. 2008; 3: 127- 16- Aduol OM, Ogila KO, John K. Evaluation of 33. antibacterial effects and phytochemiacl screening 23- Krinke GJ. History, strains and models. of the aqueous and methanolic extracts of hibiscus Thelaboratory rat hand book of experimental diversifolious. J Microbiol Antimicrobial. 2014; animals. UK: Academic Press. 2000. 6. 5: 88-93. 24- Onderoglu S, Sozer S, Mine Erbil K, Ortac R, 17- Anandh of chemical, Babu Sabitha MAM, Hussein BA, Lermioglu F. The evaluation of long-term effects Shyamaladevi CS. Green tea extract impedes of cinnamon bark and olive leaf on toxicity dislipidemia induced by streptozotocin administration to rats. J development KE, Abd-Elmageed 12. and PV, antioxidant of cardiac dysfunction in sterptozotocin in diabetic rats. Clin Pharm Exp Pharmacol physiol. 2006; 33: 1184-9. 25- Mahmood S, Talat A, Karim S, Khurshid R, Pharmacol. 1999; 51: 1305-12. æèîéŶƴƠſřƹƲưƸŝæåæƽƵŹŚưƃ çèƽƵŹ ƹŵƱŚºŬƳŻƾƳŚƯŹŵƾŤƃřŶƸŝšŚƯŶųƹƾĪƃżěƭƺƬƗƵŚĮƄƳřŵƾƄƷƹĦěƾưƬƗƽ ƶƬŬƯ Downloaded from zums.ac.ir at 11:18 IRST on Wednesday March 8th 2017 ƵŵřŻŶưŰƯƽŶƸƯźŤƧŵƹƵŵřŻƞ ƿźƃƶǀưſ Zia A. Effect of cinnamonextract on blood dephosphorylates the insulin receptor in intact glucose level and lipid profile in alloxan induced cells. FEBS Lett. 1997; 40: 37-40. diabetic rats.Pak J Physiol. 2011; 7: 18-25. 30- Kulas DT, Zhang WR. Insulin receptor 26- Karalee J, Jarvill-Taylor, Anderson RA, signaling is augmented by antisense inhibition of Graves DJ. A hydroxychlcone drived from protein tyrosine phosphatase. J Biol Chem. 1995; cinnamon functions as a mimetic for insulin in 770: 2435-8. 3t3-L1 adipocytes. J Am Coll Nutr. 2001; 20: 327- 31- Lopez P, Sanchez C, Batlle R, Nerin C. Solid- 36. and varpour- phase antimicrobial activities of six 27- Fannworth NR, Segelman AB. Hypoglycemic essential oils: susceptibility of selected foodborne plants. Tile and Till. 1971; 57: 52-6. bacterial and fungal strains. J Agric Food Chem. 28- Gray AM, Flatt PR. Action of the traditional 2005; 53: 6939-46. antidiabetic eupatoria 32- Al-JamalAR, Naji Rasheed I. Effects of (Agrimony): effects on hyperglycemia, cellular cinnamon (Cassia zelynicum) on diabetic rats. glucose metabolism and insulin secretion. Br J 2010; 4: 615-17. Nutr. 1998; 80: 109-14. 33- Rother KI. Diabetes treatment- briding the 29- Lamers R, Moller NP. The transmembrane divide. N Engl J Med. 2007; 556: 499-501. protein plant, tyrosin Agrimony phosphatase alpha æèîéŶƴƠſřƹƲưƸŝæåæƽƵŹŚưƃ çèƽƵŹ ƹŵƱŚºŬƳŻƾƳŚƯŹŵƾŤƃřŶƸŝšŚƯŶųƹƾĪƃżěƭƺƬƗƵŚĮƄƳřŵƾƄƷƹĦěƾưƬƗƽ ƶƬŬƯ źƳƽŚƷšŹ ŹŵƱƺųƭźſƾƿŚǀưǀƃƺǀŝƽŚƷźŤƯřŹŚěźŝƲǀģŹřŵƾŝōįƵŹŚƈƗ šřźŧřƾſŹźŝ The Effects of Aqueous Extract of Cinnamon on Blood Biochemical Parameters in Streptozotocin-Induced Diabetic Rats Sharifzadeh S1, Mohammadzadeh M1 Dept. of Biology, Faculty of Science, Urmia University , Urmia, Iran Downloaded from zums.ac.ir at 11:18 IRST on Wednesday March 8th 2017 1 Corresponding Author: Mohammadzadeh M, Dept. of Biology, Faculty of Science, Urmia University , Urmia, Iran. E-mail: [email protected] Received: 8 Nov 2014 Accepted: 27 Apr 2015 Background and Objective: Nowadays, the use of herbal products has been proposed as an alternative to chemical drugs. Cinnamon is considered as a beneficial and useful herb. Due to the increasing demand of medicinal plants to treat diseases and identify any side effects on different organs, this study was performed to investigate the effects of aqueous extract of cinnamon on serum biochemical parameters in streptozotocininduced (STZ) diabetic rats. Materials and Methods: 21 male Wistar rats were assigned to three groups of 7 including control, diabetic control and diabetic rats treated with the extract, respectively. Fasting mice were diabolized with 50 mg/kg intraperitoneal injection of streptozotocin. After 21 days of treatment with the extract at a dose of 200 mg/ kg, blood sugar, triglycerides, cholesterol, HDL and LDL in serum were measured in three groups. Results were analyzed using one- way ANOVA and Tukey test. Results: A significant decrease in blood glucose, triglycerides and cholesterol in the treated diabetic rats were seen whereas, there was no significant changes in LDL and HDL levels. Conclusion: Since the plants in this family have flavonoid components, their effect on reduction of serum biochemical parameters including blood glucose, triglyceride and cholesterol may be due to these components. Therefore, the aqueous extract of cinnamon has anti-diabetic properties and its proper use is beneficial for diabetic patients Keywords: Cinnamon extract, Diabetes, Rats, Biochemical parameters æèîéŶƴƠſřƹƲưƸŝæåæƽƵŹŚưƃ çèƽƵŹ ƹŵƱŚºŬƳŻƾƳŚƯŹŵƾŤƃřŶƸŝšŚƯŶųƹƾĪƃżěƭƺƬƗƵŚĮƄƳřŵƾƄƷƹĦěƾưƬƗƽ ƶƬŬƯ
