The effect of protocatechuic acid on the tongue mucosa LQ UDWV H
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The effect of protocatechuic acid on the tongue mucosa LQ UDWV H
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Y'&T %c%&[ ?H(.( #"( ##+, -* )(-*( 6 "(,+/ + +-) )/,+/ + -!3/)/()H #" H+/" !"'&&Y%&c%&[+-)R&TY']c%&[(/(*# .(,-#"(Z/#*+/( #H+// 5 ,+6#"(+- 5+,/H #"+**(,(+#()*+* -!(-(_/3(Y'&&T'Fc'F[/ !- Z*+-#, -*(+/() H"(- *5+() H #" (_*,3/ .(, `(_/() +#/ 6 #"( Z/# H((I/ 6 #"( /#3) Y\]T'<c'R[ 5 ,+)+#+H+/(#()6)/,+/ +'&&TY'Fc'F[+-)F]TY''c'R[(/(*# .(, "( *3(-# +-) +4.( 5(-# -() (#/ WR '<X +/ H(,, +/ #"( 5)(,/ 6 (_( 5(-#+,, -)3*()3 -+4,+))(W%X*,- *W'X"(+# *W'FX+-)(/"+!(+,W'&X#35 !(-(/ /.() #"+# /+-(66(*# .(*"(5(.(-# -+!(-#)3 -!4#" - # +# -+-)/# - # +# -"+/(/#H+/ /#3,+#()#"+#/3*"+*# . # /+//* +#()H #"+-# _ )+# .(+-)+-# , 6(+# .((# (/6 WR'&'<XD3#"(5(5)3,+# -6#"(+*# . #6(-M5(/ -.,.() -*+* -!(-5(#+4, /5 1 -(H((I4(6(*+* -!(-+)5 - /#+# -#"3!"3#/(.(-H((I/6`(_/3(+-) H((I+6#(#"(*+* -!(-)/+!(H+/#(5 -+#()Y''&H((I/6#"(/#3)#*,[ 2 D5'&#"#<%ndH((I6#"(/#3)#*, 190 :3/#-+M35 G,g4 (#+#+/G+H/I+?(,(-+- *+ *"+GM35 G(#+, Y (*#*"5(F& /(-M5(/[ -" 4 # -6 +))3*#/65+# -+-)(_(// -6!(-( (-!+!() -, 6(+# -+#/ /+-)+-! !(-(/ /+(+,/ 5#+-#W'&'%X #/"3,)4(5(-# -()#"+#/ 5 ,+*"(5(.(-# -+*# . # -(_( 5(-#+,+,*+* -!(-(/ / H+/ +,/ (.(+,() 6 5+- -+#3+, /-#"(# * +!(-#/ -*,3) -! *+66( * *",!(- * (,,+! * +-)6(3, *+* )/(/H(+#,"(/( ) -*3*35 -!+* -, -),(<*+4 -,) +,,,/3,Z)(!((- #(+,"(-,/B(-!"(-! -!Y5 _#3(6/ _#+) # -+," -(/("(4/[+/H(,,+/ _ *+5 - 5(/3, )#!, #+M-(W<e]''X - *-*,3/ - # *3,) 4( /#(//() #"+# / + *"(5(.(-# - +!(-# - (_( 5(-#+, +, #35 !(-(/ / - +#/ ?H(.( +)) # -+, /#3) (/ H #" ) 66((-# ,+4+# +- 5+,/ +-) #"( (*, - *+,4/(.+# -/+()(/ +4,(4(6(#"((/3,#/+(#+-/6(()#"35+-+*# *(#*3,)4( +,//#(//()#"+##"( /-#+#(-#*+* -!(-6#"(+,53*/+)3(##"(,H -* )(-*( 6-(,+/5-/3*"/#3) (/+5((66(*# .(/34/#+-*(, I(`/"3,)4(3/() REFERENCES 1. ,*I^+##(/-34+ dD3 #.(!(#+4,(/+-)*+-*((.(-# -d+(. (H6#"(( )(5 ,! *+, (. )(-*(3#+-*(']''RR% 2. ? /(@(#+,d"(5(.(-# -63 -+4,+))(*+* -!(-(/ /4#"(-+#3+,"(-, **53-) #*+#(*"3 *+* ) -+#/+* -!(-(/ /'\%<<e'RRF < +-P + + )+ d - #U3 -, -('_ )( -)3*() (_( 5(-#+, +, *+* -!(-(/ / +, -*,%\FF%&&\ 4. (. ,,((#+,() #/Y%&&R[+,+-)5+_ ,,6+* +,+#",!#3 /d+3-)(/,/(. ( 5. +*"(*+,(-* + (# +,d "(5 *+, *5/ # - +-# _ )+-# (# (/ +-) #"(5+, /#+4 , # 6+"#*"(5 *+,(- *"() ,65 *+ Y3#((,(+*(++#[: ! *D)"(5F\\<' 2008. 6. ),)H/I+:(#+,d )(5 ,! + *M-- I MI++I+P+53/#-(P,(I3(I+/I <% '<F%&'% 7. - .+/+-(#+,d"(5(.(-# .(+-)#"(+(3# *5)3,+# -6!((-#(+,"(-,/-)3! 5(#+4, M -!(-M5(/ - #U3 -, -('_ )( -)3*()+,*+-*("(5 ,-#(+*#'e% %%%&&] 8. 3-B(#+,d"(5(.(-# -6+,*+-*( -+- 5+,5)(,/+-)(66(*#-,(3I,+I +/ -"35+- +# (-#/H #"B(-!"(-! -!+5 _#3(65() * -+,"(4/+,-*,\'&F%&'& 9. 3M3I (#+,d (#+#*+#(*"3 *+* ))3 -!#"(!(// -"+/((_(#/*"(5(.(-# .( (66(*#/-*"(5 *+,, -)3*()+##-!3(*+* -!(-(/ / / +-+*:+-*((.<'R%&&< 10. M35 G : Y%&&e[ GH (/H(+#,3 IH+/3 #I+#(*"H(! -+ MHQP -H#HQH G+/I-+4G-IH*" M(GI3 3 /M*M3+ -)3IH+-*" M(M - #M5(#,4(-M,+5 -J M+H+?+4 , #+*P-+34, -d- H(/#(#()*M-H34, - ( 11. M35 G:(#+,d"(5(H(-*P+-H#HQHG+/I-+4G-IH*"P+53/#-(P4+)+- +I, - *M-( )KH +)*M+,-(,(I3(I+/I <%'<]%&'% 12. M35 G:dH+/#I+#(*"HH(H(-*P -H#HQH/#? !()/HFR\&]%&&F "((66(*#6#*+#(*"3 *+* )-#"(#-!3(53*/+ -+#/(_/() 191 '< +-+I+(#+,d"(5(.(-# -6- #U3 -, -('_ )( -)3*()+,*+* -!(-(/ /4) (#+ #*+#(*"3 *+* ))3 -! - # +# -+-)/# - # +# -"+/(/+-*((/F%<FR'RR 14. +-+I+ (# +,d "(5(.(-# - 6 *,- * *+* -!(-(/ / 4 #"( -+#3+, )3*# 6 + / 5,( "(-, **53-)#*+#(*"3 *+* )d/3(// -!(66(*#-#35)(.(,5(-#+-)4 5+I(/ (_(// -6*,-#35!(-(/ /+-*((/F<<R&]'RR< 15. +-+I+(#+,d"(5(.(-# -6) (#",- #/+5 -( -)3*()"(+#*+* -!(-(/ /4+/ 5,( "(-, *+* )#*+#(*"3 *+* ) -+#/+-*((/F<%eeF'RR< 16. "(+,+-*(D3-)+# -Y%&''[d"##dcc+,*+-*(63-)+# -!cY,+/#+**(//7(#(54('%%&''[ ABSTRACT "((66(*#6-+#3+,,+-#)( .()"(-,#*+#(*"3 *+* )-,(/ -/ -)3*()4*+* -!(- - #/5(#",4(-M,+5 -( - #"( /U3+53/ ( #"(, 35 6 #"( #-!3( H+/ -.(/# !+#() - +#/ +* -!(- H+/ +, () 6 <] H((I/ 6 #"( (_( 5(-# Y&F 5!cI!c)/(7 < )/(/cH((I[ #*+#(*"3 *+* )H+/+)5 - /#(()H #"+)+ ,) (# -#H)/(/'&&&%&&&56Z/#e %H((I/6#"((_( 5(-#-* )(-*(+-)53,# , * #6!//,(/ -/-#"()/+,/36+*(6 #"( #-!3( H+/ #"( " !"(/# - +#/ (_/() (_*,3/ .(, # *+* -!(- 3,# , * # 6 ,(/ -/ H+/ / !- Z*+-#,,H( -#"(!36()H #") (#*-#+ - -!#*+#(*"3 *+* ) -" !"()/(6#"( H",( (_( 5(-# "( 5/# 6(U3(-# ,(/ - - #"( 5 */* * (_+5 -+# - H+/ "(,+/ + 6 #"(/U3+53/( #"(, 35/,+/ ++-)+ ,,5+/H((+(,/((-H" ,(*+* -5+/H((-# 4/(.() "(5(.(-# - +*# . # 6 #*+#(*" 3* +* ) - +, () (_( 5(-#+, 5)(, H+/ *-Z5() Keywords: #*+#(*"3 * +* ) - #/5(#",4(-M,+5 -( (_( 5(-#+, *+* -!(-(/ / #-!3(+# BB +**(- -HGH-+#3+,-(!K, --(!MH OMI36(-,H(!IH+/3#I+#(*"H(! -+ MHQP M5 +- M/#H*" -+4G-I+ H (,H+/#HH(! G+/I (! !H+* (PO*(! PJMI+ -)3IH+-*" M(M I+*-!(- - #M5(#,4(-M,+5 -J 3 /M*M3QH +*-!(- )+H+-)/IQ- (H)+H*(&F5!cI!5*#M+MH#!)- 3)<)]#!)- +)KH +)*M(- + -+#5 +/# IH+/ #I+#(*"H H +/M H )+HI+*" '&&& ,34 %&&& 5 M(M (H/M( e ,34 % #!)- ( MJ/#Kt , *M4+ M5 +- 5+I/IH*" -+ H (M*"- !M4 (#H(P PJMI+ 4G+ -+PHg/M+ 3 MH (MO# #M53PO**" HGO*M- ( I+*-!(- *M4+ M5 +- 4G+ /##- ( - g/M+ H !3 (#M53PO*(PIH+/#I+#(*"HHH JI/M(P)+H*(M(M*+G()KH +)*M(- +4+)+- 3 5 I/IH5-+P*MJK* (PH/#J3PO*5 M5 +-+5 4GM/#-+4G-I+G+/I (!7)/,+MP+ 4)+H*M+I G+/I-+4G-IH(H/#JH+GM+)M (P (/#H ()M-4(*-K* +IQH+)+- + #H ()M G )M +G+- ( *"(5(H(-*P-( IH+/3 #I+#(*"H(! H M+/#/H+-5 5)(,3 )KH +)*M+,-5 IH+/ #I+#(*"H - #M5(#,4(-M,+5 -+ )KH +)*M+,-+ I+*-!(-(M+PJMI/M*M3