Wsp œwyst¸powanie objaw×w l¸ku i depresji w kolejnych
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Wsp œwyst¸powanie objaw×w l¸ku i depresji w kolejnych
ORIGINAL PAPER Curr Probl Psychiatry 2012; 13(4):231-237 ×ϸ׸ ¦Ă The comorbidity of anxiety and depression symptoms during pregnancy trimesters Justyna Morylowska-Topolska1, Marta Makara- 2 1Katedra 2Samodzielna i Klinika Psychiatrii, Uniwersytet Medyczny, Lublin Pracownia Zdrowia Psychicznego, Uniwersytet Medyczny, Lublin Cel pracy. ! " #"$ % &'*+ / !"5 6 589<5=" 5 >! "< e badanymi parametrami wykonano z wykorzystaniem " ? "@ !BDF%+H%D'%QH%ecim DQ%QH" @ % V *W%'H % *D%FH *+H" "X B'F%QH%DW%+YH"@ % i *D%FH%*[%YH*D%+H!"@ *W%QH !%**%WH"5 '%WHQ%\"? no % ! " @ 8 = ] tanu 6 89<5="6 o"6 w trzecim trymestrze. ? " ? !% B ! B "?B B o i depr! % niepra> " Ï V %%! @^" The scientific aim of this work was the assessment of anxiety and depressive symptoms in particular pregnancy trimesters and the analysis of different types of anxiety: anxiety as a state and anxiety as a trait. Material and methods. The research was conducted in gynecologic-obstetric clinics in the area of Lublin and Mazovian provinces from January 2011 to May 2012. It was longitudinal prospective trial. Each woman was examined three times: during first, second and third "_> V5questionnaire – of own construction, 9<` 5 89<5=% _ > <` ]^" < ^ utive trimesters, women were given a set of questionnaires for filling in and they returned them at next visit. The examined group consisted of 314 preg8^*Y=women. _"$>^V%dard deviation, median, minimal and maxim^"5>`^– the following nonparametric tests were used: U Mann-Whitney test and ANOVA of Kruskal-Wallis. The analysis of mutual correlation between examined parameters was performed using the Spearman range correlation test. Five percent >^>>8}=~["[W"W Results Anxiety symptoms in the first trimester of pregnancy were experienced by DF"+H of respondents, in the second trimester – by D'"QH, in the third – by DQ"QH. 5^ymptoms occurred less frequently, and so: in the first trimester in *W"'H> % in the Copyright © 2012 Medical University of Lublin 232 J. Morylowska-Topolska, M. Makara- second in *D"FH% in the third- in *+H> the women. At least once the symptoms of anxiety were experienced by 'F"QH> the respondents, depressive symptoms - by DW"+YH"Percentages of the women, in whom anxiety and depressive symptoms coexisted in different trimesters, amounted to *D"FH> the respondents in the first%*["YHand 12.4Htrimester of pregnancy. Anxiety symptoms were present in *W"QH > in all trimesters of pregnancy, and in **"WH in the two trimesters. For depression, these percentages were respectively '"WH Q"\H. The relation between the severity of symptoms of anxiety and depression severity in different trimesters was confirmed, but this relationship was stronger in the first and third trimester than in the second trimester. $ scales (anxiety as a state and as a trait) of the Inventory of State and Trait Anxiety correlated with the severity of symptoms of hospital anxiety and depression scale (9<5="Anxiety as a state most strongly correlated with symptoms of anxiety in the third trimester and with depression in the first trimester. Anxiety as a trait most strongly correlated with symptoms of anxiety and depression in the third trimester. Conclusions Introducing of screening tests regarding anxiety and depression during pregnancy, conducted systematically during this period, creates possibility for earlier diagnosis and quicker provision of appropriate interventions. Earlier diagnosis and appropriate interventions in case of anxiety and depression development during pregnancy creates a possibility of preventing their effects, such as postpartum depression and disturbed psychophysical development of child. : anxiety, depression, pregnancy ¸ ? B a e o"! By*" Nowsze badania, opublikowane po roku 2000 do % ! ! ! yD" X ! ! o c %!" $ !% ! oogicznym dystresem u matki w okresie o '"?<i 8D[[F= B% ! e ! ! i !% +" %!e ! ! a% !i% % d!a % rel - oW" ? W[H b % % % %>zna czy zesp - " ?o %k % y ! Curr Probl Psychiatry 2012; 13(4):231-237 ! w% powo> \" ? o !" b ! ! 8 – – cecha). Ï $ ogiczno-! mazowieckim w okresie od stycznia 201* D[*D"$ i 8B% _% 6 % 5 # % 6= B 86=" o *Y–+W ! –! w!" X $#68[DW+FFD[**=" $ i% ! Vw%! kontrolnych w gabinecie ginekologiczno-!" ? V i 6 5 89<5=% ] i Cechy L 8_<]=aficzny. 6 5 89<5=% a- ? ! ! " ! akt " ? 9<5 B%" % % " 5 % ! ! ! ewag% ! B % ! a ! " Bu " @ ! podskali od 0–F !%Y–10 % **–14 pkt. – % *W–21 – za ! F" ] " In 6 8_<]= –Trait Anxiety Inventory (STAI) – opracowanego w przez %68*QF[="< _<] V erger, Strelau, Tysarczyk ?B 8*QYF=Y" $ ] ! B a 8 – stan) oB (lek – =Y" V dskala X-* ! – % B X-2 do ba – " ! D["< % w podskali X-* B teraz, w tym momencie, a w podskali X-D "? B D[ 8 =Y[k8 =" X wynikami uzyskanymi w obu ska ! owych na steny. Kwestionariusz demograficzno – epidemiologicz V %%! % zamieszka% " X w! B z > psychicznych. ?WW[ / !" _ / cz '*\ " ? > e " > y u ego ! " ? 233 314 kobiet. Uzyskane wyniki poddano analizie staty"< i "XB8}=[%[W" Analizy statystyczne przeprowadzono w oparciu \" ?!Y\8DF%+H= 6 5 89<5=" X! 8++& *+%[H= 8'Y& *D%*H=" + 8*%'H= o ! " o 8FW& D'%QH= dodatni wynik w podskali l 9<5"!a! 8WD& *\%\H= 8D[&\%+H=" ' 8[%QH= ! " ? ! DQ%QH 8Q+= 9<5"B 8+Y& *W%'H= 8+[&*D%YH="\8*%QH= kobiet wy ! " B !% tryme !" 9<5 dla pierw% V \%*' 8'%++=%W%F[ 8'%[Q=\%'[ 8'%WW=" *W%QH8W[= / !" **%WH 8'\= a B %*[%WH8''= " ? !% ! / kowych B!'F%QH8**Q=" ? 9<5 ! +Y 8*W%'H= " $ 8+'&*'%FH="+8*%'H= o%8[%'H=! " ? +[ 8*D%FH= 9<5"Xa! ! 8'W& **%*H=" W 8*%\H= r " ! anych nie ! " ? ! *+H 8++= 9<5" 5 'W8**%*H= % Y – de 8D%\H=% 8[%'H= – ! " y !% Curr Probl Psychiatry 2012; 13(4):231-237 234 J. Morylowska-Topolska, M. Makara- trymestrach. Wyso B 8D*%\H=% 8*\%\H=" B / 8+*%*H= w pierwszym trymestrze (3F%'H=" ? B w pierw8*D%FH=% tryme8Q%\H=" B 8WF%[H= w po ugiego trymestru 8WW%*H=8_]=" !" 9<5 % V '%Q\ 8D%YQ=%'%Y* 8D%FY=+%*D 8D%QY=" '%W H 8**= !" Q%\H badanych 8'[= B % *D%+H 8'Q= y "? !% ! BDW%+YH8Y[="6 *D%FH 8+[= % *[%YH 8'+= tryme*D%+H8'Q=!" _]" ]6 8_<]= Zmienna L-stan (X-1) L-cecha (X-2) II trymestr III trymestr N I trymestr H N H N H niski 117 37,3 *DQ 41,1 121 'Y%W *DQ 41,1 133 42,3 130 41,4 wysoki \Y D*%\ WD *\%\ \' 20,1 niski 173 WW%* 173 WW%* *FQ WF%[ 101 32,2 111 'W%' QF '[%Q wysoki 40 12,7 30 Q%\ 'Y 12,1 Wynik N– liczba badanych _]]"? - 9<58 6 5e= 9<5! 1 5]estrze 5]]estrze 5]]]estrze [%F\ [%W\ [%WQ 6 ] 6 ]] [%WQ [%F* [%+Q 6 ]]] [%\[ [%+Q [%F+ ȗ~[%[W a depresynych w poszc 8_ ]]=" Stwierdzono istotne statystycznie dodatnie korela 9<5 !"X a ecim trymestrze (Tabela II). @ ami uzyska ] 6 " Curr Probl Psychiatry 2012; 13(4):231-237 zedstawiona w Tabelach III i IV. Stwierdzono istotne statystycznie dodatnie kore 9<5 ] _<] w pierwszym trymestrze, drugim i trzecim trymestrze. 9<5 ] _<] obserwowano w trzecim trymestrze. 5 e 9<5 a w pierwszym trymestrze (Tabela III). ? ! D'W _ ]]]" ? -Spearmana 9<5 8 6 5= -1 (L-=]6 8_<]=e! L-stan w I trymestrze L-stan w II trymestrze L-stan w III trymestrze 6 ] [%\\ [%W+ [%WQ 6 ]] [%+Q [%\\ [%+\ 6 ]]] [%W\ 0,47 0,70 5]estrze [%\' [%+\ [%W' 5]]estrze [%+W [%WQ 0,41 5]]]estrze [%W' [%+W 0,\[ ȗ~[%[W _]"? - 9<58 6 5= -2 (L-=_<]]6 ych trymestrach ! L-cecha w I trymestrze L-cecha w II trymestrze L-cecha w III trymestrze 6 ] 0,70 [%WY [%WY 6 ]] [%WQ [%\' 0,42 6 ]]] [%WQ [%+Y [%\\ 5]estrze [%\' [%W[ [%W[ 5]]estrze [%W+ [%WW [%'\ 5]]]ymestrze [%W' 0,43 [%W+ ȗ~[%[W Stwierdzono istotne statystycznie dodatnie ko 9<5 i wyni hy Inwentarza STAI w pierwszym trymestrze, drugim i trzecim trymestrze. obserwowano w pierwszym trymestrze (Tabela IV). $ % ! / dzono do niedawna, ! hroni kobiet przed zaQ" h ! % ! ego ! w % % ! zabu ! niedo *[" dono !! orodo**" X ! % ! B ! ! !"Xa!/ X"aniu $ 8D[[W= *D" % B e!% ! ! B cze" ? e ! " / B ! ! '[H% ! D[H" ? *Y%QH " 5 ! ikami *'" ?!%! a % ! oB 'F%QH % DW%+H"! !i ! 6 " W tamtym badaniu, przeprowadzonym w 2007 roku, ! B ! W+H%'F%*H*'" D[[+ $ / % B B aCurr Probl Psychiatry 2012; 13(4):231-237 D'\ J. Morylowska-Topolska, M. Makara- nia de F%+H (2,2-*D%\H=% u *D%YH8*[%F-*+%YH=% *D%[H8F%+-*\%FH=*+"? e !" ! B% ! % u e! % a % !h metod diagnostycznych, o czym Bd ! ! w danym trymestr" a ! Be% !% o e>a !" $ # " 8D[['= % ! a ! ! B e > " B !oB B *W" ! !% !% " ? B !" ]6 % n ! / B o 8 – = B 8 – =Y" ? B e 8D*%\H=% 8*\%\H= B 8*D%FH=%8Q%FH=" Xa!B a % ! B oB " ? !B 6 5 ystkich trymestrach. Przy czym 6 5 e !% trymestrze. Obie podskale Inwentarza Stanu i Cechy Curr Probl Psychiatry 2012; 13(4):231-237 6 a "] i midzy innymi Field i wsp. (2002), Sutter-58D[[+= 68D[[F=*'%*\%*F" ? B !!o> e!B !" 1. ! / ! zB s B ! B owania. 2. ?B B o e ! % raz > cka. 1. 6 ]"% X _#"% 9 #" X epression: "X"D[[F&WD8Y=V+FQ– +YY" 2. 6"% #"% $ ?" " > epression during pregnancy following antidepressant discontinuation: a preliminary prospective study. Arch ?#9D[[+&F8+=VD*F–221. 3. ^"%9"%X""5^ptoms during pregnancy and low birth weight at term: longitu"$ X"D[[F&*Q*VY+–YW" 4. Alder J., Fink N., $ " et al. 5 `iety during pregnancy: a risk factor for obstetric, fetal and neonatal outcome? A critical review of the literature. J Matern Fetal Neonatal Med"D[[F&D[8'=V*YQ–D[Q" W" Field T., 5 #., 9-Reif M. et al. Chronic prenatal depression and neonatal outcome. Int J Neurosci. D[[Y&**Y8*=VQW–103. \" "% " 6 % _rmedi%XD[*[" 7. 9"% <"% $"% " anie 6 5– 9<5atycz"XX"*QQ\&'[8+=V\W'–\\Y" Y" ?B "% _"% <" " ] 6 _<]" X ? ! Q" 10. 11. 12. 13. 14. _<]" X % X _ Xogicznych, ?D[[\" 5"%#6"%#"5gnancy XD[[W&W*V*[YF–*[Q'" @9 #?" % > ^% ssion during pregnancy and the puerperium. Arch Gen Psy"*QY\&+'VW\Q–WF'" > <"% $ "% " " X^ > epressive symptoms in late pregnancy and postpartum. <@"D[[*&Y[8'=VDW*–DWW" $ @"% # <"% 5^ <" " atal outcomes in offspring of women with anxiety and depres " < ? # 9 D[[W&YV*Y*–*YQ" Lee AM., Keung Lam S., Sze Mun Lau SM. et al. Prevalence, Course Risk Factors for Antenatal Anxiety and 5ssion, Obstet. Gnecolo" D[[F& **[8W=V **[D– 1112. $ 9<"% <"% _ <% " X^alence of depression during pregnancy: systematic review. Obstet "D[[+&*['8+=V\QY–F[Q" *W" *\" 17. 237 ##"%9<"%$"""5^ptoms among pregnant women screened in obstetrics "?9"D[['&*D8+=V'F'–Y[" _"% 5 #"% 9-Reif M. Prenatal depression effects on the foetus and neonate in different ethnic and socio-economic status groups. J Repr Inf Psychology 2002,20: *+Q–*WF Sutter-5 <6"% Giaconne-Marcesche V., Glatigny 5 "% et al. Women with anxiety disorders during pregnancy are at increased risk of intense postnatal depressive symptoms: A prospective survey of the MAT]5"Eur Psychiatry 2004; *QV+WQ–+\'" Justyna Morylowska-Topolska Klinika Psychiatrii UM w Lublinie " *%D[-442 Lublin V @op.pl . Curr Probl Psychiatry 2012; 13(4):231-237