Palenie marihuany a ryzyko ponownej hospitalizacji psychiatrycznej
Transkrypt
Palenie marihuany a ryzyko ponownej hospitalizacji psychiatrycznej
ʹͲͳ͵ǢͳͶȋͳȌǣʹͻǦ͵ Palenie marihuany a ryzyko ponownej hospitalizacji psychiatrycznej chorych na schizofreni Ǧ ÏÏ ͳǡǡÏʹǡǡ ×ʹǡ͵ǡǡ Ͷǡ Streszczenie ¸ä ¸ǡĂ Ă × ×Ǥ Ϧ ¦ ¦ ¦ ¦¸ÑǦ Ǥ × Ñ ¦ ¦× ¸ ¦ ÏĂ ǤĂ ¦ ¸ä ¦ ¦Ï× ¸Ǧ Ǥ ¦ǡĂĂ© Ǧ ǤÏ Ï ä ǡÏĂǦ ä©¦Ñ¸Ă ¦Ǥ ¦ ¦× Ǧ ¦×Ǥä¸ǡæà Ǧ ¸¦×Ï ¦ × ǡ Ă©¸ Ǥ Ǧ ¦ǡĂĂ©Ï ǡ Ï© ÑǤ Sowa kluczeǣ ǡǡ Abstract ǡ Ǥ Ǥ ǡ ǡ Ǥǡ Ȃ Ǧ Ȃ Ǥ Ǥ ǡ Ǥ Ǥǡ ǯ ǡ Ǥ Ǧ ǡ Ǥ Keywordsǣ ǡ ǡ Wstp Ï ǡ × Ǧ ͶͲͲͲ ȏͳȐǤ ¦ǡ Ǧ ¦ æ ¦ Ï ä ȏʹȐǤǡøà ¸ ͳͷǦ͵Ͳ ȏʹȐǤ×Ăǡ ¸ Ă ¦Ă ȏʹǡ͵ȐǤ ̹ʹͲͳ͵ ×Ă ¸ä Ă Ǧ ä× × ¸ ȏͶȐǤ ¸Ǧ × × ȏͷȐǤ ¦ Ǥ Ǧ ǡ Ă ä× × ¸ ¦ Ă ä ʹΨǡ Ǧ ä ͳ Ψ × ȏȐǤ ¦ ä× × Ï ¸ ͵Ͳ ǤÏ ǡǤÏǡǤ×ǡǤ ǤǤǡĂ ¦ ¦ ͷͳΨ ä× Ï ¸ ȏȐǤ͵Ψ ×ĂǦ Ïǡ͵ʹΨ¦ÏȏͺȐǤ ¦ ä© Ă ¦×¸ ¦ȏͻȐǤ Ăä© Ïǡ Ă Ǧ ¦ Ǥ×ǡĂ ×ǡ× ¸¦ × Ǧ Ǥ Ăä© Ïǡ Ă ȏͻȐǤ Ï × Ă © ×Ă ä ×Ï Ǧ ȏͳͲȐǤ ¸ ǡ Ï Ǧ ¦ ¸ Ǧ ȏͳͳǡͳʹȐǤ ä× ¸ ǡ ¸ ¦ ä ¦ Ǧ ǡ ¸ ×Ă ĂǦ ǡ ȏͳ͵ȐǤ Przyczyny palenia marihuany wród pacjentów chorych na schizofreni Ñ × ¸ ¦ ¸ ǡ Ă × Ï × ȏͳͶǡͳͷǡͳǡͳǡͳͺǡͳͻȐǤ ǡ Ă ¦ ¸ Ă Ƿ ¦ ä©dzǡ Ƿ¦ dzǡ Ƿ ¦ ¸ dzǡ Ƿ¦dzǡǷ ¦¸ Ǧ dzǡ Ƿ¦ ¸ dz ȏͳͶǡͳǡͳͺȐǤ Ǧ ×ĂǡĂǦ Ï ǡ ǡ Ă Ï ¸ © ¦ ¦ ¸¦ ä© Ï ¦ ȏͳǡͳͺȐǤ Ǧ Ǥ ͳͳΨ × Ïǡ Ă Ï× ÑȏͳͻȐǤ×Ă Ñ Ï × ä© ȏͳͶǡͳǡͳͺȐǤ ×Ă Ï Ǧ Ǥ Ǥ ͶʹΨ Ïǡ Ă × ǡ ͻΨ Ǧ Ï ǡ ͶΨ Ï Ƿdz ȏͳͺȐǤ ×Ă Ǥ ¸Ǧ ä© × ¦ ¸ Ï Ǧ Ï ×ǡ ǡ ¸ ¸ Ƿdz ʹͲͳ͵ǢͳͶȋͳȌǣʹͻǦ͵ ȏͳͻȐǤ × Ǧ ¦ ×Ă ¸ǡ Ă Ă © ¦ × Ǧ Ǥ ͺΨ ͵ͺΨ × Ïǡ Ă × Ǧ ȏͳͶǡͳǡͳͺǡͳͻȐǤ Neurobiologiczne efekty palenia marihuany Ï× Ǧ ¦ ͻǦ ȋȌǡ ǡ ͺǦ ǡ Ǧ ȏʹͲȐǤ ä© Ï ͲǡʹǦͲǡ͵Ψ Ǥ Ǧ Ă © ʹͲΨ ȏʹͳȐǤ Ï ¸ × ǡ Ǧ ×ǡ × ¦ Ï × ȏʹʹȐǤ Ǧ ¦ ͳ ʹȏʹ͵ǡʹͶȐǤ ͳ ¦ Ï× ×ǡ ¦ ×ǡ Ï ȏʹͷǡʹǡʹǡʹͺǡʹͻȐǤ ʹ ¸ Ï ä ȏʹͺǡ͵ͲȐǤ Ï ¦ ¦ × Ă ȏʹͺǡ͵ͳǡ͵ʹǡ͵͵ǡ͵Ͷǡ͵ͷȐǤä×× Ǧ × ͳ ¸ ¸ ǡ Ā× ȋ ǦÏǡ ǡ ǡ ǡ Ǧ ǡ Ǧ Ǧ Ǧ ǡ Ǧ Ȍǡ ǡÏǦ ǡ ¦ ×ǡ ǡ Ï ¸ ¸ǡ Ï ä ȏ͵ͷȐǤ Ï Ï Ï Ǧ ȏ͵ͷȐǤ ×Ǧ ȏʹͺǡ͵Ȑǡ ä ×Ǧ ǦǦ Ïȏ͵ǡ͵ͺǡ͵ͻǡͶͲȐǤ ¸ ǡ Ă Ǧ Ă Ï© ¸ × ¦ ×Ǧ ×ȏͶͳǡͶʹȐǤ¸ǡĂ ͻǦ ȏͶ͵ȐǤ¦ǡĂÏ ×× Ǧ ¸ǤǤ¦¸ä© ¸ä ¸ ¸ ȏͶͶȐǤ Ǥ ¸ä ¸ä ¸ ¸ ×צ ¦ Ǧ ȏͶͷȐǤ Ǥ ¦ ¸ä©Ï×ĂĂʹ͵ǤͻΨ Ǧ ǡʹͻǡΨ¦ ¸ Ǧ ¸ǡ × ¦ ȏͶȐǤ ǡ Ă Ǧ ¦ ¦ ¸ä ¦ ×ĂĂȏͶȐǤǤǦ ×Ă ¸ä ×ǡ ×ĂĂ ×׸ Ǧ ¸ ¦ Ă ǡ ĂȏͶͺȐǤ Ǥ ×Ă × ¦ Ǧ ¸ × ¦ Ǥ ¸ ¸ ¸ × × ¦ Ă × ¦ ȏͶͻȐǤǦ ¦ǡ Ă ×ǡ¸¦ Ǧ ͳ ¸ ȏͶͶǡͶͷȐǡǦ ÏȏͷͲǡͷͳȐ×ĂĂȏͶǡͷͳȐǤ Palenie marihuany a ryzyko nawrotu psychozy u osób chorych na schizofreni ä ¦ ¸ ×Ǧ Ǥ Ñ ǡ Ă ǡ Ǧ ä ×Ă × Ǧ Ïä ǡ ǡ Ă Ǥ ǡ Ă ȏͳ͵ȐǤ Ǥ ǡ Ă Ă ǡ Ï ¸ä© ͳʹ ¸ Ǥ ×Ă Ǧ ¦×Ă ¸Ïä ¸ ¸ ¦ ǡ æ Ǥ×Ă Ǧ Ï ¸ ¸ ×Ă Ă Ă ×ȏͷʹȐǤ¦ Ǥǡ × ×Ă ¸ ä× × × ¦ ǡ ×Ă × ¸ × ȏͷ͵ȐǤ ä ǡ × × ¸¦ ¸× Ǧ ͵ͳ × × ¦ Ǥ ×Ǧ Ăǡ Ă Ă ä Ǧ Ă ǡ ¦ ¸ × ¸Ï ä Ï ¸ × × ¦ Ǥ Ăä© Ï ¸ Ǧ Ă Ă Ǧ ×ȏͷͶȐǤ Palenie marihuany, wpyw na objawy chorobowe a ryzyko hospitalizacji Ǥ ¦ × × ¸ ǡĂ¸× ¸Ï ȏͷͷȐǤ ×Ă Ïǡ Ă Ǧ Ï ¦ ¸ ȏͷȐǤ ¦ ¸× ȏͷȐǤ ¦ ¦ ¸ × Ǧ Ï × Ǥ Ǥ ĂǦ Ï ¦ Ǧ × ȏͷͺȐǤ ×Ă Ǥ Ǥ¦ȏͷͻǡͲȐǤ Ǥ ä×צ צ ȏͳȐǤ×Ă ǤǡĂ ¦Ǧ ȏʹȐǤ Ǥ ¦ Ï ͳͲ ǡ Ă Ï ¦ ¸× Ă ä Ǧ Ï ¦ ¸Ă × × ȏ͵ȐǤ Ñ ¦ ¸ Ă ¦ × Ǧ ȏͲȐǤ Ï ȏͷͻǡʹǡ͵ǡͶǡȐǤ Ǥ ǡĂ ¸ × ¸ ǡ ä ¸ Ƿä©dz ȏͷȐǤ Ï ¦ ¸ Ǧ × ¸ × ¸ ȏͳǡͶȐǤ Ǧ ʹͲͳ͵ǢͳͶȋͳȌǣʹͻǦ͵ ͵ʹ ǤÏ ǡǤÏǡǤ×ǡǤ ¸¦ ¸ȏʹȐǤǦ ǤǡĂ Ǧ Ï Ǥ ¦ Ǧ ¸×ĂĂ ¦ ×צ ȏȐǤ×Ǧ ¦ǡĂ Ǧ × ¸ ¦ ¸ ¦ Ïǡ ¸ ǡ× ǡ Ă ǡǡǦ ¸dz ¸ × ÏȏǡͺȐǤ¦×Ǧ Ăǡ Ă ¸ ¦ Ǧ ¸ ¸ä ȏͶǡͻȐǤ Ǥ ×Ă ¸¦ Ǧ ¸ ¦ ¸ ǡ ä Ă ¸ × Ǥ ×Ă Ăä ¸ × Ǧ ä ¦Ă ä ¦Ǧ ȏͷʹȐǤǤǦ ¦ ¸ ͳʹͲʹ × ¦ ¸ Ă ×ǡ ¸ ǡ Ǧ ¸ ȏͲȐǤ Palenie marihuany, stosowanie si do zalece lekarskich a ryzyko ponownej hospitalizacji ¦ǡ Ă ¸ Ñ Ă × ¸¦ ȏͳǡʹǡ͵ȐǤ Ǥǡø Ñ × ȏͶȐǤǤ ǡĂ×Ï ¦ ͶͲΨ × ȏͷȐǤ Ǥ ǡĂ ×Ï ¦ ʹǡͶ ¸ä Ǧ Ñ ǡ ÏÏĂȏ͵ȐǤ ¦ ¸ä© ä× ××Ï ¦Ǧ ȏȐǤ Ǥ ǡ Ă¦Ï¦×Ï ¦ × ¸ ȏͲȐǤ ×ĂǤĂ ʹͲͳ͵ǢͳͶȋͳȌǣʹͻǦ͵ Ï ×Ï ȏȐǤ Ǧ ǤǡĂ Ǧ Ï ¦ ¦ ×Ï ¦ ȏͺȐǤ × Ǥ ×Ă ¸ä × ¸ ¦ ¸ × ¦ 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ǤǡǤǡǤǡǤǡ Ǥǡ Ǥǡ Ǥǡ Ǥǡ Ǥǣ Ǥ ǤͳͻͻͺǢ ͻͺȋʹȌǣͳͷȂͳͶ ͺͺǤ Ǧ Ǥǡ Ǥǡ Ǥǡ Ǥǡ Ǥǣ Ǥ ǤʹͲͲͶǢͳͺͷǣʹͳͷȂʹͳͻǤ ͺͻǤ ǤǡǤǡǤǡǤǡ ǤǡǤ Ǥ Ǥ Ǥ ʹͲͳͲǢ ͳͺͲȋʹǦ͵Ȍǣ ͶȂͻǤ ͻͲǤ Ǥǡ Ǥǡ Ǥǡ Ǥǡ ǡ Ǥ ͳͻǤ ǤʹͲͲǢʹʹȋʹȌǣͳʹͻǦͳ͵ ͻͳǤ Ǥǡ Ǥǡ Ǥǡ Ǥǡ Ǥǡ Ǥǡ ǤǡǤ ǣǤ ǤʹͲͲͶǢͻͻȋͶȌǣͶʹͷǦͶ͵ͲǤ ͺͷǤ ǤǡǤǡǤǡǤǡ Ǥǡ Ǥ ǤʹͲͲǢͺ͵ȋͳȌǣͷ͵Ȃ͵Ǥ Ǥ Ǥ ʹͲͲͻǢ ͶʹȋȌǣ ͺ͵Ǥ Ǥǡ Ǥǡ Ǥǡ Ǥǡ Ǥǣ Ǥ Ǥ Ǥǡ ǦǤǡ Ǥǡ Ǥǡ Ǥǡ Ǥǣ Ǥ Ǥǡ Ǥǡ Ǥǡ Ǥǡ Ǥǡ Ǥǡ Ǥǡ Ǥǡ Ǥǡ Ǥǡ Ǥǡ ǣ Ǥ Ǧ ǣ Ǧ Ǧ Ǥ Ǥǡ¡ǣ Ǥ ǤͳͻͻǢͶͲȋͳͳȌǣͳͳͷͷȂͳͳ͵Ǥ Ǥ Ǥ ʹͲͲͳǢ ͺͲǤ ͵ Ǥǡ Ǥ Ǧ ǣ ǡ ǡ Ǥ ǤʹͲͲͷǢ͵ͳȋ͵ȌǣͷͲǦͳǤ ͻʹǤ Ǥǡ Ǥǡ Ǥ ʹͲͳ͵ǢͳͶȋͳȌǣʹͻǦ͵